Cyclic Nucleotide Phosphodiesterases, Type 4

"Cyclic Nucleotide Phosphodiesterases, Type 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cyclic nucleotide phosphodiesterase subfamily that is found predominantly in inflammatory cells and may play a role in the regulation of CELL-MEDIATED IMMUNITY. The enzyme family includes over twenty different variants that occur due to multiple ALTERNATIVE SPLICING of the mRNA of at least four different genes.

Descriptor ID	D054703
MeSH Number(s)	D08.811.277.352.640.150.400 D12.644.360.008.400 D12.776.476.008.400
Concept/Terms	Cyclic Nucleotide Phosphodiesterases, Type 4 Cyclic Nucleotide Phosphodiesterases, Type 4 Phosphodiesterase-4 Phosphodiesterase IV PDE4 Phosphodiesterases Phosphodiesterases, PDE4 Cyclic Nucleotide Phosphodiesterase PDE4 Family Phosphodiesterase 4 Type 4 Cyclic Nucleotide Phosphodiesterase Cyclic Nucleotide Phosphodiesterases, Type 4A5 Cyclic Nucleotide Phosphodiesterases, Type 4A5 cAMP-Specific Phosphodiesterase 4A5 Phosphodiesterase 4A5, cAMP-Specific cAMP Specific Phosphodiesterase 4A5 Cyclic Nucleotide Phosphodiesterases, Type 4D3 Cyclic Nucleotide Phosphodiesterases, Type 4D3 PDE4D3 Phosphodiesterase Phosphodiesterase, PDE4D3 Cyclic Nucleotide Phosphodiesterases, Type 4C Cyclic Nucleotide Phosphodiesterases, Type 4C Phosphodiesterase 4C Cyclic Nucleotide Phosphodiesterases, Type 4D Cyclic Nucleotide Phosphodiesterases, Type 4D Phosphodiesterase 4D Cyclic Nucleotide Phosphodiesterases, Type 4A Cyclic Nucleotide Phosphodiesterases, Type 4A Phosphodiesterase 4A Cyclic Nucleotide Phosphodiesterases, Type 4B Cyclic Nucleotide Phosphodiesterases, Type 4B Phosphodiesterase 4B

Below are MeSH descriptors whose meaning is more general than "Cyclic Nucleotide Phosphodiesterases, Type 4".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Phosphoric Diester Hydrolases [D08.811.277.352.640]
3',5'-Cyclic-AMP Phosphodiesterases [D08.811.277.352.640.150]
Cyclic Nucleotide Phosphodiesterases, Type 4 [D08.811.277.352.640.150.400]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
3',5'-Cyclic-AMP Phosphodiesterases [D12.644.360.008]
Cyclic Nucleotide Phosphodiesterases, Type 4 [D12.644.360.008.400]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
3',5'-Cyclic-AMP Phosphodiesterases [D12.776.476.008]
Cyclic Nucleotide Phosphodiesterases, Type 4 [D12.776.476.008.400]

Below are MeSH descriptors whose meaning is related to "Cyclic Nucleotide Phosphodiesterases, Type 4".

Below are MeSH descriptors whose meaning is more specific than "Cyclic Nucleotide Phosphodiesterases, Type 4".

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