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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. PLoS Genet. 2013; 9(2):e1003222.
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PubMed
subject areas
African Americans
African Americans
Alleles
Alleles
Antigens, Nuclear
Antigens, Nuclear
Apoptosis
Apoptosis
Autoantibodies
Autoantibodies
Chromosome Mapping
Chromosome Mapping
DEAD-box RNA Helicases
DEAD-box RNA Helicases
DNA-Binding Proteins
DNA-Binding Proteins
Genetic Predisposition to Disease
Genetic Predisposition to Disease
Genome, Human
Genome, Human
Haplotypes
Haplotypes
Humans
Humans
Inflammation
Inflammation
Interferon-Induced Helicase, IFIH1
Interferon-Induced Helicase, IFIH1
Ku Autoantigen
Ku Autoantigen
Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
Polymorphism, Single Nucleotide
Polymorphism, Single Nucleotide
Protein Binding
Protein Binding
authors with profiles
Patrick Gaffney
Joan Merrill
Judith A James
Swapan K. Nath
R Hal Scofield