Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.

Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons. Mol Cancer Ther. 2006 Jan; 5(1):29-38.

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subject areas

Adaptor Proteins, Signal Transducing
Animals
Apoptosis
ATPases Associated with Diverse Cellular Activities
Cysteine Proteinase Inhibitors
HeLa Cells
Humans
Leupeptins
LIM Domain Proteins
Mitosis
Nocodazole
Paclitaxel
Peptide Fragments
Proteasome Endopeptidase Complex
Proteasome Inhibitors
Protein Kinases
RNA, Small Interfering
Spindle Apparatus
Transcription Factors

authors with profiles

Gary J Gorbsky
Hiroshi Yamada