"beta 2-Microglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
| Descriptor ID |
D001613
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| MeSH Number(s) |
D12.776.124.790.223.100 D12.776.377.715.182.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta 2-Microglobulin".
Below are MeSH descriptors whose meaning is more specific than "beta 2-Microglobulin".
This graph shows the total number of publications written about "beta 2-Microglobulin" by people in this website by year, and whether "beta 2-Microglobulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta 2-Microglobulin" by people in Profiles.
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Biomarker panel for early detection of endometrial cancer in the Prostate, Lung, Colorectal, and Ovarian cancer screening trial. Am J Obstet Gynecol. 2019 11; 221(5):472.e1-472.e10.
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Comparison of cystatin C and Beta-2-microglobulin kinetics in children on maintenance hemodialysis. Hemodial Int. 2013 Oct; 17 Suppl 1:S11-6.
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Real-time measurement of in vitro peptide binding to soluble HLA-A*0201 by fluorescence polarization. Biochemistry. 2004 Nov 23; 43(46):14852-63.
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Immune protection and control of inflammatory tissue necrosis by gamma delta T cells. J Immunol. 1994 Oct 01; 153(7):3101-15.
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[Manifestations of dysfunction of the proximal tubules after intravenous urography]. Vnitr Lek. 1990 Feb; 36(2):141-6.
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[Plasma and synovial beta-2-microglobulin. Results of a personal study]. Rev Rhum Mal Osteoartic. 1985 Oct; 52(10):549-54.