"Lipoprotein Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.
Descriptor ID |
D008071
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MeSH Number(s) |
D08.811.277.352.100.430
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Concept/Terms |
Lipoprotein Lipase- Lipoprotein Lipase
- Lipase, Lipoprotein
- Diglyceride Lipase
- Lipase, Diglyceride
- Heparin-Clearing Factor
- Factor, Heparin-Clearing
- Heparin Clearing Factor
- Post-Heparin Lipase
- Lipase, Post-Heparin
- Post Heparin Lipase
- Postheparin Lipase
- Lipase, Postheparin
- Postheparin Lipoprotein Lipase
- Lipase, Postheparin Lipoprotein
- Lipoprotein Lipase, Postheparin
- Diacylglycerol Lipase
- Lipase, Diacylglycerol
- Lipemia-Clearing Factor
- Factor, Lipemia-Clearing
- Lipemia Clearing Factor
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Below are MeSH descriptors whose meaning is more general than "Lipoprotein Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipoprotein Lipase".
This graph shows the total number of publications written about "Lipoprotein Lipase" by people in this website by year, and whether "Lipoprotein Lipase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 0 | 1 |
2002 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipoprotein Lipase" by people in Profiles.
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Lipoprotein Lipase Overexpression in Skeletal Muscle Attenuates Weight Regain by Potentiating Energy Expenditure. Diabetes. 2021 04; 70(4):867-877.
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Placental lipoprotein lipase activity is positively associated with newborn adiposity. Placenta. 2018 04; 64:53-60.
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Lipolysis, and not hepatic lipogenesis, is the primary modulator of triglyceride levels in streptozotocin-induced diabetic mice. Arterioscler Thromb Vasc Biol. 2015 Jan; 35(1):102-10.
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Lipoprotein abnormalities in compound heterozygous lipoprotein lipase deficiency after treatment with a low-fat diet and orlistat. J Clin Lipidol. 2013 Mar-Apr; 7(2):132-9.
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Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues. Diabetes. 2009 Jan; 58(1):116-24.
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Downregulated IRS-1 and PPARgamma in obese women with gestational diabetes: relationship to FFA during pregnancy. Am J Physiol Endocrinol Metab. 2002 Mar; 282(3):E522-33.
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Genetic screening of the lipoprotein lipase gene for mutations associated with high triglyceride/low HDL-cholesterol levels. Hum Genet. 2000 Sep; 107(3):257-67.
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Lipopolysaccharide regulation of lipoprotein lipase expression in murine macrophages. Infect Immun. 1995 Mar; 63(3):858-64.
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In vitro and in vivo analysis of murine lipoprotein lipase gene promoter: tissue-specific expression. Am J Physiol. 1995 Feb; 268(2 Pt 1):E213-8.
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Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein. J Cell Biochem. 1994 Jan; 54(1):122-33.