Proto-Oncogene Proteins c-jun
"Proto-Oncogene Proteins c-jun" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.
| Descriptor ID |
D016755
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| MeSH Number(s) |
D12.776.260.108.820 D12.776.624.664.700.182 D12.776.660.763 D12.776.930.127.820
|
| Concept/Terms |
Proto-Oncogene Proteins c-jun- Proto-Oncogene Proteins c-jun
- Proto Oncogene Proteins c jun
- c-jun Proteins
- c jun Proteins
- fos-Associated Protein p39
- fos Associated Protein p39
- jun Proto-Oncogene Product p39
- jun Proto Oncogene Product p39
- jun Proto-Oncogene Proteins
- jun Proto Oncogene Proteins
- p39 c-jun
- p39 c jun
- p39(c-jun)
- Proto-Oncogene Products c-jun
- Proto Oncogene Products c jun
- c-fos-Associated Protein p39
- c fos Associated Protein p39
- Proto-Oncogene Proteins jun
- Proto Oncogene Proteins jun
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-jun".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-jun".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-jun" by people in this website by year, and whether "Proto-Oncogene Proteins c-jun" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-jun" by people in Profiles.
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Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer. Oncotarget. 2016 Nov 08; 7(45):72845-72859.
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Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer. Oncogene. 2016 11 03; 35(44):5795-5806.
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Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals. FEBS Lett. 2005 Jun 06; 579(14):3152-8.
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Upregulation of the matrix metalloproteinase-1 gene by the Ewing's sarcoma associated EWS-ER81 and EWS-Fli-1 oncoproteins, c-Jun and p300. FEBS Lett. 2003 Oct 09; 553(1-2):104-8.
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Adenovirus-mediated mda-7 gene expression radiosensitizes non-small cell lung cancer cells via TP53-independent mechanisms. Mol Ther. 2002 Nov; 6(5):637-44.
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Early molecular changes in bladder hypertrophy due to bladder outlet obstruction. Urology. 2002 Jun; 59(6):978-82.
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Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2. Mol Cell Biol. 1999 May; 19(5):3423-34.
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Different binding specificities and transactivation of variant CRE's by CREB complexes. Nucleic Acids Res. 1994 Apr 25; 22(8):1463-9.
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Heterodimer formation between CREB and JUN proteins. Oncogene. 1990 Mar; 5(3):295-302.