Proto-Oncogene Proteins pp60(c-src)
"Proto-Oncogene Proteins pp60(c-src)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.
Descriptor ID |
D016392
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MeSH Number(s) |
D08.811.913.696.620.682.725.800.630 D12.776.624.664.700.202
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Concept/Terms |
Proto-Oncogene Proteins pp60(c-src)- Proto-Oncogene Proteins pp60(c-src)
- Phosphoprotein pp60(c-src)
- pp60 c-src
- c-src, pp60
- pp60 c src
- pp60(c-src)
- Proto-Oncogene Protein src
- Protein src, Proto-Oncogene
- Proto Oncogene Protein src
- src Proto-Oncogene Product
- Proto-Oncogene Product, src
- src Proto Oncogene Product
- src Proto-Oncogene Protein pp60
- src Proto Oncogene Protein pp60
- c-src Protein pp60
- Protein pp60, c-src
- c src Protein pp60
- pp60, c-src Protein
- Proto-Oncogene Protein pp60(c-src)
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins pp60(c-src)".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins pp60(c-src)".
This graph shows the total number of publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in this website by year, and whether "Proto-Oncogene Proteins pp60(c-src)" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1997 | 2 | 0 | 2 |
2000 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in Profiles.
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Imatinib binding to human c-Src is coupled to inter-domain allostery and suggests a novel kinase inhibition strategy. Sci Rep. 2016 08 02; 6:30832.
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Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer. Sci Rep. 2015 May 14; 5:10194.
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Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2. J Cell Sci. 2009 Sep 15; 122(Pt 18):3385-92.
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Expression of N-myristoyltransferase inhibitor protein and its relationship to c-Src levels in human colon cancer cell lines. Biochem Biophys Res Commun. 2000 Jul 14; 273(3):1116-20.
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Activation-induced bi-dentate interaction of SHIP and Shc in B lymphocytes. J Cell Biochem. 1997 Oct 01; 67(1):32-42.
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Activation of pp60c-src is necessary for human vascular smooth muscle cell migration. Surgery. 1997 Aug; 122(2):138-44; discussion 144-5.
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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature. 1995 Jun 15; 375(6532):577-81.