Phosphatidylinositol 3-Kinases
"Phosphatidylinositol 3-Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.
| Descriptor ID |
D019869
|
| MeSH Number(s) |
D08.811.913.696.620.500
|
| Concept/Terms |
Phosphatidylinositol 3-Kinases- Phosphatidylinositol 3-Kinases
- Phosphatidylinositol 3 Kinases
- Phosphoinositide 3-Hydroxykinase
- PI 3-Kinase
- PtdIns 3-Kinases
- 3-Kinases, PtdIns
- PtdIns 3 Kinases
- PI-3K
- PI3 Kinases
- Kinases, PI3
- PI3-Kinase
- PtdIns 3-Kinase
- Phosphatidylinositol-3-OH Kinase
- PI-3 Kinase
|
Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol 3-Kinases".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol 3-Kinases".
This graph shows the total number of publications written about "Phosphatidylinositol 3-Kinases" by people in this website by year, and whether "Phosphatidylinositol 3-Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 2 | 1 | 3 |
| 2002 | 5 | 5 | 10 |
| 2003 | 5 | 3 | 8 |
| 2004 | 2 | 2 | 4 |
| 2005 | 2 | 6 | 8 |
| 2006 | 2 | 2 | 4 |
| 2007 | 1 | 2 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 3 | 5 |
| 2010 | 4 | 3 | 7 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 4 | 5 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 2 | 3 | 5 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 4 | 4 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Phosphatidylinositol 3-Kinases" by people in Profiles.
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Ribosomal targeting strategy and nuclear labeling to analyze photoreceptor phosphoinositide signatures. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 08; 1867(8):159161.
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A randomized phase II trial of everolimus and letrozole or hormonal therapy in women with advanced, persistent or recurrent endometrial carcinoma: A GOG Foundation study. Gynecol Oncol. 2022 03; 164(3):481-491.
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Insulin signaling alters antioxidant capacity in the diabetic heart. Redox Biol. 2021 11; 47:102140.
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Sclerosing Polycystic Adenoma: Conclusive Clinical and Molecular Evidence of Its Neoplastic Nature. Head Neck Pathol. 2022 Jun; 16(2):416-426.
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Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family. Fam Cancer. 2022 07; 21(3):347-355.
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Naproxen inhibits spontaneous lung adenocarcinoma formation in KrasG12V mice. Neoplasia. 2021 06; 23(6):574-583.
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Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model. Physiol Rep. 2021 01; 8(24):e14672.
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Novel targetable biomarkers in clear cell carcinoma of the breast uncovered by molecular profiling: A study of nine cases. Breast J. 2020 09; 26(9):1781-1783.
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. Cell Rep. 2019 08 13; 28(7):1860-1878.e9.
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The driver landscape of sporadic chordoma. Nat Commun. 2017 10 12; 8(1):890.