"Zinc Finger Protein GLI1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional activator and oncogene protein that contains two CYS2-HIS2 ZINC FINGERS. Two isoforms are expressed; both regulate the expression of specific genes during development of craniofacial features, digits, the CENTRAL NERVOUS SYSTEM; and the GASTROINTESTINAL TRACT. They also regulate SONIC HEDGEHOG PROTEIN signaling and cell proliferation.
Descriptor ID |
D000071676
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MeSH Number(s) |
D12.776.260.755.850 D12.776.624.664.700.989 D12.776.930.900.700
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Concept/Terms |
Zinc Finger Protein GLI1- Zinc Finger Protein GLI1
- Oncogene GLI Protein
- GLI Protein, Oncogene
- Glioma-Associated Oncogene Protein
- Glioma Associated Oncogene Protein
- Oncogene Protein, Glioma-Associated
- Gli Protein
- Gli1 Protein
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Below are MeSH descriptors whose meaning is more general than "Zinc Finger Protein GLI1".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger Protein GLI1".
This graph shows the total number of publications written about "Zinc Finger Protein GLI1" by people in this website by year, and whether "Zinc Finger Protein GLI1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Zinc Finger Protein GLI1" by people in Profiles.
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The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex. J Biol Chem. 2020 02 28; 295(9):2698-2712.
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EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells. Nat Commun. 2017 06 12; 8:15773.
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The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells. Reproduction. 2009 Aug; 138(2):329-39.