"Steroid 21-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
| Descriptor ID |
D013255
|
| MeSH Number(s) |
D08.244.453.493.500 D08.244.453.915.760 D08.811.682.690.708.170.463.500 D08.811.682.690.708.170.915.760 D12.776.422.220.453.493.500 D12.776.422.220.453.915.760
|
| Concept/Terms |
Steroid 21-Hydroxylase- Steroid 21-Hydroxylase
- Cytochrome P-450 21-Hydroxylase
- Cytochrome P 450 21 Hydroxylase
- Cytochrome P-450(c-21)
- Progesterone 21-Hydroxylase
- Progesterone 21 Hydroxylase
- Cytochrome P-450 CYP21
- Cytochrome P 450 CYP21
- Steroid 21-Monooxygenase
- Steroid 21 Monooxygenase
- Cytochrome P450c21
- Cytochrome P-450 c21
- Cytochrome P 450 c21
- P-450 c21, Cytochrome
- 21-Hydroxylase
- 21 Hydroxylase
- Steroid-21-Hydroxylase
- Steroid 21 Hydroxylase
|
Below are MeSH descriptors whose meaning is more general than "Steroid 21-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Steroid 21-Hydroxylase".
This graph shows the total number of publications written about "Steroid 21-Hydroxylase" by people in this website by year, and whether "Steroid 21-Hydroxylase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Steroid 21-Hydroxylase" by people in Profiles.
-
Leptin receptor antagonist treatment ameliorates the effects of long-term maternal hypoxia on adrenal expression of key steroidogenic genes in the ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2013 Mar 15; 304(6):R435-42.
-
Prevalence of CYP21 mutations and IRS1 variant among women with polycystic ovary syndrome and adrenal androgen excess. Fertil Steril. 2005 Feb; 83(2):371-5.
-
Inter- and intrafamilial variability in premature pubarche and polycystic ovary syndrome. Fertil Steril. 2002 Sep; 78(3):473-8.
-
Candidate gene analysis in premature pubarche and adolescent hyperandrogenism. Fertil Steril. 2001 Apr; 75(4):724-30.
-
The role of heterozygosity for CYP21 in the polycystic ovary syndrome. J Pediatr Endocrinol Metab. 2000; 13 Suppl 5:1315-7.
-
Genetic mapping of the 21-hydroxylase locus: estimation of small recombination frequencies. Am J Hum Genet. 1988 Sep; 43(3):304-10.
-
A segregation and linkage study of classical and nonclassical 21-hydroxylase deficiency. Am J Hum Genet. 1988 Jun; 42(6):830-8.