| Item Type | Name |
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Concept
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Animals
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Concept
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Anti-Inflammatory Agents
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Concept
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Cadmium
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Concept
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Calcium
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Concept
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Amino Acid Sequence
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Concept
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Amino Acids
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Concept
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Carboxylic Ester Hydrolases
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Concept
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B-Lymphocytes
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Concept
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Base Sequence
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Concept
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Catalysis
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Concept
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Cattle
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Concept
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Cell Cycle
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Concept
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Cell Line
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Concept
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Cell Nucleus
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Concept
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Cytochrome c Group
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Concept
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Cytosol
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Concept
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Binding Sites
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Concept
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Binding, Competitive
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Concept
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Dendritic Cells
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Concept
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Chromatin
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Concept
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Chromatography, Gel
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Concept
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Chromogenic Compounds
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Concept
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Circular Dichroism
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Concept
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Crystallization
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Concept
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Cloning, Molecular
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Concept
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Cysteine
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Concept
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Eye Proteins
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Concept
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Female
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Concept
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Enzyme Activation
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Concept
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Dose-Response Relationship, Drug
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Concept
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Escherichia coli
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Concept
|
High Mobility Group Proteins
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Concept
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Cyclic GMP
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Concept
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Histidine
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Concept
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Electrophoresis, Polyacrylamide Gel
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Concept
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Electrophysiology
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Concept
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Histones
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Concept
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Horses
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Concept
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Humans
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Concept
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Gene Expression Regulation
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Concept
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Hydrogen Bonding
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Concept
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Hydrolysis
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Concept
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Ligands
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Concept
|
Light
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Concept
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Lipopolysaccharides
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Concept
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Liposomes
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Concept
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Kidney
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Concept
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Glutathione Transferase
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Concept
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Kinetics
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Concept
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Lung
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Concept
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Lymphocytes
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Concept
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Lysine
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Concept
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Glycosylation
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Concept
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Inflammation
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Concept
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Intermediate Filament Proteins
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Concept
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Mutation
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Concept
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Nuclear Proteins
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Concept
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Nucleic Acid Conformation
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Concept
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Nucleic Acids
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Concept
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Ions
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Concept
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Nucleotides
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Concept
|
Isoelectric Point
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Concept
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Nerve Tissue Proteins
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Concept
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Plasmids
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Concept
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Plasminogen
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Concept
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Mice, Inbred C57BL
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Concept
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Microscopy, Fluorescence
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Concept
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Polymers
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Concept
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Models, Biological
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Concept
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Models, Molecular
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Concept
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Molecular Sequence Data
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Concept
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Phosphoserine
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Concept
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Regulatory Sequences, Nucleic Acid
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Concept
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Scattering, Radiation
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Concept
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Peptide Fragments
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Concept
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Endopeptidases
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Concept
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Peptides
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Concept
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Purines
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Concept
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Pyrimidines
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Concept
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T-Lymphocytes
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Concept
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Radiation, Ionizing
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Concept
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Temperature
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Concept
|
Transcription Factors
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Concept
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Transfection
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Concept
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Thermodynamics
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Concept
|
Receptors, Antigen
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|
Concept
|
Recombinant Fusion Proteins
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Concept
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Recombinant Proteins
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Concept
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Recombination, Genetic
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|
Concept
|
Zinc
|
|
Concept
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Blotting, Western
|
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Concept
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Cytochromes b5
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|
Concept
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Protozoan Proteins
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Concept
|
Streptokinase
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|
Concept
|
Structure-Activity Relationship
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Concept
|
Gene Rearrangement
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Concept
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Titrimetry
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|
Concept
|
Subcellular Fractions
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|
Concept
|
Substrate Specificity
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|
Concept
|
Sequence Homology, Amino Acid
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Concept
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Protein Structure, Secondary
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Concept
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Protein Structure, Tertiary
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Concept
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Protein Folding
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Concept
|
Vitamin A
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Concept
|
Conserved Sequence
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Concept
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Centrosome
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Concept
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Homeodomain Proteins
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Concept
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Pliability
|
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Concept
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Microscopy, Confocal
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Concept
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Mutagenesis
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Concept
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Mutagenesis, Site-Directed
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Concept
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Zinc Fingers
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Concept
|
Mutation, Missense
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Concept
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Catalytic Domain
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|
Concept
|
rab5 GTP-Binding Proteins
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|
Concept
|
ADP-Ribosylation Factors
|
|
Concept
|
Surface Plasmon Resonance
|
|
Concept
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DNA, Complementary
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|
Concept
|
Amino Acid Motifs
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Concept
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Protein Structure, Quaternary
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Concept
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Helix-Loop-Helix Motifs
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Concept
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Mice, Knockout
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Concept
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Crystallography, X-Ray
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|
Concept
|
Saccharomyces cerevisiae Proteins
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|
Concept
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cis-trans-Isomerases
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|
Concept
|
Pressure
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|
Concept
|
Amino Acid Substitution
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Concept
|
Protein Binding
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|
Concept
|
Protein Conformation
|
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Concept
|
Protein-Tyrosine Kinases
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Concept
|
Proteins
|
|
Concept
|
Protein Interaction Mapping
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Concept
|
F-Box Proteins
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Concept
|
SKP Cullin F-Box Protein Ligases
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Concept
|
Toll-Like Receptor 4
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Concept
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Mice
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Concept
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Rats
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|
Concept
|
GRB10 Adaptor Protein
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Concept
|
Spectrophotometry
|
|
Concept
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Spectrum Analysis, Raman
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|
Concept
|
Cyclic Nucleotide-Gated Cation Channels
|
|
Concept
|
Biocatalysis
|
|
Concept
|
Trypsin
|
|
Concept
|
Opsins
|
|
Concept
|
Lung Injury
|
|
Concept
|
Protein Stability
|
|
Concept
|
Gene Expression
|
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Concept
|
Vesicular Transport Proteins
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|
Concept
|
Adaptor Proteins, Vesicular Transport
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|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Tetraspanins
|
|
Concept
|
Cytokines
|
|
Concept
|
V(D)J Recombination
|
|
Concept
|
Pulmonary Surfactant-Associated Protein A
|
|
Concept
|
Pulmonary Surfactant-Associated Protein D
|
|
Concept
|
Aspartic Acid Endopeptidases
|
|
Concept
|
Retinal Cone Photoreceptor Cells
|
|
Concept
|
Leukemia Inhibitory Factor Receptor alpha Subunit
|
|
Concept
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Oncostatin M Receptor beta Subunit
|
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Concept
|
Oncostatin M
|
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Concept
|
Dimerization
|
|
Concept
|
Computational Biology
|
|
Concept
|
Amyloid Precursor Protein Secretases
|
|
Concept
|
DNA Cleavage
|
|
Concept
|
DNA Breaks, Double-Stranded
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
Hydrophobic and Hydrophilic Interactions
|
|
Concept
|
Protein Subunits
|
|
Concept
|
Protein Transport
|
|
Concept
|
Protein Sorting Signals
|
|
Concept
|
Active Transport, Cell Nucleus
|
|
Concept
|
Precursor Cells, B-Lymphoid
|
|
Concept
|
Ataxia Telangiectasia Mutated Proteins
|
|
Concept
|
Peripherins
|
|
Concept
|
Electrophoretic Mobility Shift Assay
|
|
Concept
|
VDJ Recombinases
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Maltose-Binding Proteins
|
|
Concept
|
Macromolecular Substances
|
|
Concept
|
Multiprotein Complexes
|
|
Concept
|
Static Electricity
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Cell Survival
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Chickens
|
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Concept
|
Dictyostelium
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|
Concept
|
Disease Models, Animal
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|
Concept
|
Diterpenes
|
|
Concept
|
DNA
|
|
Concept
|
DNA Damage
|
|
Concept
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DNA Mutational Analysis
|
|
Concept
|
DNA Nucleotidyltransferases
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Concept
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DNA Repair
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|
Concept
|
DNA-Binding Proteins
|
|
Concept
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DNA, Single-Stranded
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|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Fungal Proteins
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Membrane Lipids
|
|
Concept
|
Membrane Proteins
|
|
Concept
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Metals
|
|
Concept
|
Methionine
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|
Concept
|
Oligonucleotides
|
|
Concept
|
Osmolar Concentration
|
|
Academic Article
|
The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer.
|
|
Academic Article
|
Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase.
|
|
Academic Article
|
Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins.
|
|
Academic Article
|
Characterization of Lys-698-to-Met substitution in human plasminogen catalytic domain.
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Academic Article
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Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1.
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Academic Article
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DNA cleavage activity of the V(D)J recombination protein RAG1 is autoregulated.
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Academic Article
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DNA cleavage of a cryptic recombination signal sequence by RAG1 and RAG2. Implications for partial V(H) gene replacement.
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Academic Article
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Thermal dependency of RAG1 self-association properties.
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Academic Article
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A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor.
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Academic Article
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Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS.
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|
Academic Article
|
Glycosylation of Skp1 affects its conformation and promotes binding to a model f-box protein.
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Academic Article
|
A zinc-binding domain involved in the dimerization of RAG1.
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Academic Article
|
A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2.
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Academic Article
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A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity.
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Academic Article
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Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding.
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Academic Article
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Mapping electrostatic interactions in macromolecular associations.
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Academic Article
|
DNA binding and bending by the transcription factors GAL4(62*) and GAL4(149*).
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|
Academic Article
|
Identification of two topologically independent domains in RAG1 and their role in macromolecular interactions relevant to V(D)J recombination.
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Academic Article
|
Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5.
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Academic Article
|
The disease-causing mutations in the carboxyl terminus of the cone cyclic nucleotide-gated channel CNGA3 subunit alter the local secondary structure and interfere with the channel active conformational change.
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|
Academic Article
|
Riches in RAGs: Revealing the V(D)J Recombinase through High-Resolution Structures.
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|
Academic Article
|
A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2.
|
|
Academic Article
|
Binding to lipid membrane induces conformational changes in RPE65: implications for its isomerohydrolase activity.
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|
Academic Article
|
Spatio-temporal regulation of RAG2 following genotoxic stress.
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|
Academic Article
|
An interdomain boundary in RAG1 facilitates cooperative binding to RAG2 in formation of the V(D)J recombinase complex.
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Academic Article
|
RAG2 localization and dynamics in the pre-B cell nucleus.
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|
Academic Article
|
Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster.
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|
Grant
|
Deciphering DNA sequence selectivity in V(D)J recombination
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|
Grant
|
Protein-DNA Interactions in V(D)J Recombination
|
|
Grant
|
Nuclear export-dependent functions of RAG2 in the DNA damage response system
|
|
Grant
|
Regulation of the VDJ recombinase during genotoxic stress
|
|
Grant
|
Single cell visualization of the V(D)J recombinase complex
|
|
Academic Article
|
Full length RAG2 expression enhances the DNA damage response in pre-B cells.
|
|
Academic Article
|
Mechanism of Anti-Inflammatory Activity of TLR4-Interacting SPA4 Peptide.
|
|
Academic Article
|
Effects of SPA4 peptide on lipopolysaccharide-disrupted lung epithelial barrier, injury, and function in a human cell system and mouse model of lung injury.
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|
Academic Article
|
An updated definition of V(D)J recombination signal sequences revealed by high-throughput recombination assays.
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|
Academic Article
|
Stability and structure-activity relationship of the SPA4 peptide under ambient and stressed conditions of lung injury.
|
|
Academic Article
|
Molecular Mechanisms of DNA Sequence Selectivity in V(D)J Recombination.
|
|
Grant
|
DNA sequence selectivity in conventional and aberrant V(D)J recombination
|