"Enzyme Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
| Descriptor ID |
D004789
|
| MeSH Number(s) |
G02.111.263 G03.328
|
| Concept/Terms |
Enzyme Activation- Enzyme Activation
- Activation, Enzyme
- Activations, Enzyme
- Enzyme Activations
|
Below are MeSH descriptors whose meaning is more general than "Enzyme Activation".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Activation".
This graph shows the total number of publications written about "Enzyme Activation" by people in this website by year, and whether "Enzyme Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 4 | 4 |
| 1995 | 0 | 5 | 5 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 6 | 6 |
| 1998 | 0 | 8 | 8 |
| 1999 | 0 | 10 | 10 |
| 2000 | 0 | 8 | 8 |
| 2001 | 0 | 10 | 10 |
| 2002 | 0 | 10 | 10 |
| 2003 | 0 | 11 | 11 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 8 | 8 |
| 2006 | 0 | 10 | 10 |
| 2007 | 0 | 6 | 6 |
| 2008 | 0 | 6 | 6 |
| 2009 | 0 | 9 | 9 |
| 2010 | 0 | 8 | 8 |
| 2011 | 1 | 10 | 11 |
| 2012 | 0 | 7 | 7 |
| 2013 | 1 | 5 | 6 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 6 | 6 |
| 2016 | 0 | 5 | 5 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Enzyme Activation" by people in Profiles.
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DARPP32, a target of hyperactive mTORC1 in the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2022 08 16; 119(33):e2207489119.
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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression. Gastroenterology. 2021 11; 161(5):1584-1600.
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Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice. Int J Mol Sci. 2020 Dec 22; 22(1).
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Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening. SLAS Discov. 2021 01; 26(1):113-121.
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Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer. FASEB J. 2020 09; 34(9):12024-12039.
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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial. J Clin Oncol. 2019 03 20; 37(9):741-750.
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Linaclotide Attenuates Visceral Organ Crosstalk: Role of Guanylate Cyclase-C Activation in Reversing Bladder-Colon Cross-Sensitization. J Pharmacol Exp Ther. 2018 08; 366(2):274-281.
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Polyionic complexes of butyrylcholinesterase and poly-l-lysine-g-poly(ethylene glycol): Comparative kinetics of catalysis and inhibition and in vitro inactivation by proteases and heat. Chem Biol Interact. 2017 Sep 25; 275:86-94.
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Tyrosine Kinase Inhibitors Protect the Salivary Gland from Radiation Damage by Inhibiting Activation of Protein Kinase C-d. Mol Cancer Ther. 2017 09; 16(9):1989-1998.
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The effects of Ficus carica on the activity of enzymes related to metabolic syndrome. J Food Drug Anal. 2018 01; 26(1):201-210.