| Item Type | Name |
|
Concept
|
Neuroprotection
|
|
Concept
|
X-Box Binding Protein 1
|
|
Concept
|
Superoxide Dismutase-1
|
|
Concept
|
Bevacizumab
|
|
Concept
|
Brimonidine Tartrate
|
|
Concept
|
Beclin-1
|
|
Concept
|
Bestrophins
|
|
Concept
|
Netrin-1
|
|
Concept
|
Animals
|
|
Concept
|
Animals, Newborn
|
|
Concept
|
Aged
|
|
Concept
|
Aged, 80 and over
|
|
Concept
|
Antibodies
|
|
Concept
|
Alcohol Dehydrogenase
|
|
Concept
|
Alcohol Oxidoreductases
|
|
Concept
|
Histocompatibility Antigens Class II
|
|
Concept
|
Antioxidants
|
|
Concept
|
Capillaries
|
|
Concept
|
Capillary Permeability
|
|
Concept
|
Cardiovascular Agents
|
|
Concept
|
Blood-Retinal Barrier
|
|
Concept
|
Body Weight
|
|
Concept
|
beta-Galactosidase
|
|
Concept
|
Cilia
|
|
Concept
|
Dextrans
|
|
Concept
|
Diabetes Mellitus
|
|
Concept
|
Diabetes Mellitus, Experimental
|
|
Concept
|
Cobalt
|
|
Concept
|
Diabetic Retinopathy
|
|
Concept
|
Cysteine Endopeptidases
|
|
Concept
|
Color Vision Defects
|
|
Concept
|
Endoplasmic Reticulum
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Doxycycline
|
|
Concept
|
Epithelial Cells
|
|
Concept
|
Electroretinography
|
|
Concept
|
Humans
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Heme
|
|
Concept
|
Light
|
|
Concept
|
Ketocholesterols
|
|
Concept
|
Glutathione Synthase
|
|
Concept
|
Kinetics
|
|
Concept
|
Lysosomes
|
|
Concept
|
Macular Degeneration
|
|
Concept
|
Inflammation
|
|
Concept
|
Insulin
|
|
Concept
|
Muscle, Smooth, Vascular
|
|
Concept
|
Ischemia
|
|
Concept
|
Neovascularization, Pathologic
|
|
Concept
|
Nerve Growth Factors
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Microtubule-Associated Proteins
|
|
Concept
|
Mitochondria
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Mosaicism
|
|
Concept
|
Retinaldehyde
|
|
Concept
|
Retinitis Pigmentosa
|
|
Concept
|
Retinoids
|
|
Concept
|
Retinopathy of Prematurity
|
|
Concept
|
Rhodopsin
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Rod Cell Outer Segment
|
|
Concept
|
Quinoxalines
|
|
Concept
|
Rabbits
|
|
Concept
|
Radiation Injuries, Experimental
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Rats, Inbred BN
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Biomarkers
|
|
Concept
|
Receptor, Insulin
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Ion Channel Gating
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Cell Hypoxia
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Transducin
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Apoptosis
|
|
Concept
|
Rod Opsins
|
|
Concept
|
Oxidants
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Cell Death
|
|
Concept
|
Laser Coagulation
|
|
Concept
|
Vision, Ocular
|
|
Concept
|
Vitamin A
|
|
Concept
|
Patch-Clamp Techniques
|
|
Concept
|
Spodoptera
|
|
Concept
|
Disease Progression
|
|
Concept
|
ATP-Binding Cassette Transporters
|
|
Concept
|
Leukostasis
|
|
Concept
|
Mutagenesis
|
|
Concept
|
Neuroprotective Agents
|
|
Concept
|
Fluorescent Antibody Technique, Indirect
|
|
Concept
|
Tight Junctions
|
|
Concept
|
Ischemic Preconditioning
|
|
Concept
|
Brain-Derived Neurotrophic Factor
|
|
Concept
|
Sirolimus
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Antimutagenic Agents
|
|
Concept
|
Fluorescein-5-isothiocyanate
|
|
Concept
|
Choroidal Neovascularization
|
|
Concept
|
Pericytes
|
|
Concept
|
rac GTP-Binding Proteins
|
|
Concept
|
Receptors, Kainic Acid
|
|
Concept
|
Chloride Channels
|
|
Concept
|
Receptor, trkB
|
|
Concept
|
rac1 GTP-Binding Protein
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Neurodegenerative Diseases
|
|
Concept
|
Caenorhabditis elegans Proteins
|
|
Concept
|
Ryanodine Receptor Calcium Release Channel
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Receptors, G-Protein-Coupled
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Calcium Signaling
|
|
Concept
|
Potassium Channels, Voltage-Gated
|
|
Concept
|
Ubiquitin-Activating Enzymes
|
|
Concept
|
Ubiquitin-Protein Ligases
|
|
Concept
|
Apoptosis Regulatory Proteins
|
|
Concept
|
bcl-X Protein
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
beta Catenin
|
|
Concept
|
NF-E2-Related Factor 2
|
|
Concept
|
Mice
|
|
Concept
|
Rats
|
|
Concept
|
Heme Oxygenase-1
|
|
Concept
|
Cyclic Nucleotide-Gated Cation Channels
|
|
Concept
|
Retinal Pigment Epithelium
|
|
Concept
|
Night Vision
|
|
Concept
|
Opsins
|
|
Concept
|
Cone Opsins
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Retinal Neovascularization
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Cluster Analysis
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
Lentivirus
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
Free Radical Scavengers
|
|
Concept
|
Endoplasmic Reticulum Stress
|
|
Concept
|
Fibroblast Growth Factor 2
|
|
Concept
|
Wnt Signaling Pathway
|
|
Concept
|
Connexins
|
|
Concept
|
Vascular Endothelial Growth Factor Receptor-1
|
|
Concept
|
Vascular Endothelial Growth Factor Receptor-2
|
|
Concept
|
Inositol 1,4,5-Trisphosphate Receptors
|
|
Concept
|
Tomography, Optical Coherence
|
|
Concept
|
Leukemia Inhibitory Factor
|
|
Concept
|
DNA Primers
|
|
Concept
|
Retinal Cone Photoreceptor Cells
|
|
Concept
|
NADPH Oxidases
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Arrestin
|
|
Concept
|
Atherosclerosis
|
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
|
Concept
|
Integrases
|
|
Concept
|
Geographic Atrophy
|
|
Concept
|
COS Cells
|
|
Concept
|
Cytoprotection
|
|
Concept
|
Wet Macular Degeneration
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Mice, 129 Strain
|
|
Concept
|
Cytokine Receptor gp130
|
|
Concept
|
Occludin
|
|
Concept
|
Protein Transport
|
|
Concept
|
Intravitreal Injections
|
|
Concept
|
Phosphatidylinositol 3-Kinase
|
|
Concept
|
Class Ia Phosphatidylinositol 3-Kinase
|
|
Concept
|
Adrenergic alpha-2 Receptor Agonists
|
|
Concept
|
Microarray Analysis
|
|
Concept
|
Microscopy, Electron, Transmission
|
|
Concept
|
Aryl Hydrocarbon Receptor Nuclear Translocator
|
|
Concept
|
Hypoxia-Inducible Factor 1
|
|
Concept
|
Von Hippel-Lindau Tumor Suppressor Protein
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Real-Time Polymerase Chain Reaction
|
|
Concept
|
Primary Cell Culture
|
|
Concept
|
NADPH Oxidase 4
|
|
Concept
|
Aorta
|
|
Concept
|
Autophagy
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Docosahexaenoic Acids
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescein Angiography
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Infant, Newborn
|
|
Concept
|
Membrane Potentials
|
|
Concept
|
Oxygen
|
|
Academic Article
|
Mouse opsin promoter-directed Cre recombinase expression in transgenic mice.
|
|
Academic Article
|
Loss of BCL-XL in rod photoreceptors: Increased susceptibility to bright light stress.
|
|
Academic Article
|
Targeted expression of Cre recombinase to cone photoreceptors in transgenic mice.
|
|
Academic Article
|
Inducible expression of cre recombinase in the retinal pigmented epithelium.
|
|
Academic Article
|
Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage.
|
|
Academic Article
|
Effect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats.
|
|
Academic Article
|
Transcriptional code and disease map for adult retinal cell types.
|
|
Academic Article
|
Interruption of Wnt signaling in Müller cells ameliorates ischemia-induced retinal neovascularization.
|
|
Academic Article
|
Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia.
|
|
Academic Article
|
Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice.
|
|
Academic Article
|
Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency.
|
|
Academic Article
|
G protein-coupled receptor 91 signaling in diabetic retinopathy and hypoxic retinal diseases.
|
|
Academic Article
|
Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function.
|
|
Academic Article
|
Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1 alpha expression in photoreceptors.
|
|
Academic Article
|
DHA does not protect ELOVL4 transgenic mice from retinal degeneration.
|
|
Academic Article
|
Expression of Cre recombinase in retinal Müller cells.
|
|
Academic Article
|
Preconditioning-induced protection of photoreceptors requires activation of the signal-transducing receptor gp130 in photoreceptors.
|
|
Academic Article
|
Temporal requirement of RPE-derived VEGF in the development of choroidal vasculature.
|
|
Academic Article
|
Significance of outer blood-retina barrier breakdown in diabetes and ischemia.
|
|
Academic Article
|
Impacts of hypoxia-inducible factor-1 knockout in the retinal pigment epithelium on choroidal neovascularization.
|
|
Academic Article
|
RPE barrier breakdown in diabetic retinopathy: seeing is believing.
|
|
Academic Article
|
Autophagy protects the retina from light-induced degeneration.
|
|
Academic Article
|
Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration.
|
|
Academic Article
|
Müller Glia Are a Major Cellular Source of Survival Signals for Retinal Neurons in Diabetes.
|
|
Academic Article
|
Functions of Müller cell-derived vascular endothelial growth factor in diabetic retinopathy.
|
|
Academic Article
|
Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium.
|
|
Academic Article
|
VEGF production and signaling in Müller glia are critical to modulating vascular function and neuronal integrity in diabetic retinopathy and hypoxic retinal vascular diseases.
|
|
Academic Article
|
Conditional gene knockout system in cone photoreceptors.
|
|
Academic Article
|
Loss of neuroprotective survival signal in mice lacking insulin receptor gene in rod photoreceptor cells.
|
|
Academic Article
|
Phosphoinositide 3-kinase signaling in retinal rod photoreceptors.
|
|
Academic Article
|
Suppression of retinal neovascularization by lentivirus-mediated netrin-1 small hairpin RNA.
|
|
Academic Article
|
7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B.
|
|
Academic Article
|
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1.
|
|
Academic Article
|
Simplified system to investigate alteration of retinal neurons in diabetes.
|
|
Academic Article
|
Investigating the role of retinal Müller cells with approaches in genetics and cell biology.
|
|
Academic Article
|
Efficient induction of productive Cre-mediated recombination in retinal pigment epithelium.
|
|
Academic Article
|
Corneal Epithelial Cells Exhibit Myeloid Characteristics and Present Antigen via MHC Class II.
|
|
Academic Article
|
Role of BCL-XL in photoreceptor survival.
|
|
Academic Article
|
Müller cell-derived VEGF is a significant contributor to retinal neovascularization.
|
|
Academic Article
|
Computer-assisted semi-quantitative analysis of mouse choroidal density.
|
|
Academic Article
|
Deletion of the p85alpha regulatory subunit of phosphoinositide 3-kinase in cone photoreceptor cells results in cone photoreceptor degeneration.
|
|
Academic Article
|
Normoxic activation of hypoxia-inducible factors in photoreceptors provides transient protection against light-induced retinal degeneration.
|
|
Academic Article
|
VEGF as a Trophic Factor for Müller Glia in Hypoxic Retinal Diseases.
|
|
Academic Article
|
Loss of X-box binding protein 1 in Müller cells augments retinal inflammation in a mouse model of diabetes.
|
|
Academic Article
|
Noninvasive Diagnosis of Regional Alteration of Retinal Morphology and Structure with Optical Coherence Tomography in Rodents.
|
|
Academic Article
|
Critical Role of Trophic Factors in Protecting Müller Glia: Implications to Neuroprotection in Age-Related Macular Degeneration, Diabetic Retinopathy, and Anti-VEGF Therapies.
|
|
Academic Article
|
VEGF Mediates Retinal Müller Cell Viability and Neuroprotection through BDNF in Diabetes.
|
|
Academic Article
|
VEGF as a Direct Functional Regulator of Photoreceptors and Contributing Factor to Diabetes-Induced Alteration of Photoreceptor Function.
|
|
Academic Article
|
Critical Role of VEGF as a Direct Regulator of Photoreceptor Function.
|