Proto-Oncogene Proteins c-akt
"Proto-Oncogene Proteins c-akt" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
| Descriptor ID |
D051057
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.755 D12.776.476.565 D12.776.624.664.700.168
|
| Concept/Terms |
Proto-Oncogene Proteins c-akt- Proto-Oncogene Proteins c-akt
- Proto Oncogene Proteins c akt
- c-akt, Proto-Oncogene Proteins
- Protein Kinase B
- Proto-Oncogene Protein RAC
- Proto Oncogene Protein RAC
- RAC, Proto-Oncogene Protein
- Proto-Oncogene Protein Akt
- Akt, Proto-Oncogene Protein
- Proto Oncogene Protein Akt
- Rac Protein Kinase
- akt Proto-Oncogene Protein
- Protein, akt Proto-Oncogene
- Proto-Oncogene Protein, akt
- akt Proto Oncogene Protein
- RAC-PK Protein
- RAC PK Protein
- Related to A and C-Protein
- Related to A and C Protein
- c-akt Proto-Oncogene Protein
- Protein, c-akt Proto-Oncogene
- Proto-Oncogene Protein, c-akt
- c akt Proto Oncogene Protein
- c-akt Protein
- Protein-Serine-Threonine Kinase (Rac)
Proto-Oncogene Proteins c-akt1- Proto-Oncogene Proteins c-akt1
- Proteins c-akt1, Proto-Oncogene
- Proto Oncogene Proteins c akt1
- c-akt1, Proto-Oncogene Proteins
- AKT1 Protein Kinase
- Rac-PK alpha Protein
- Rac PK alpha Protein
- alpha Protein, Rac-PK
- Protein Kinase B alpha
- Akt-alpha Protein
- Akt alpha Protein
Proto-Oncogene Proteins c-akt2- Proto-Oncogene Proteins c-akt2
- Proteins c-akt2, Proto-Oncogene
- Proto Oncogene Proteins c akt2
- c-akt2, Proto-Oncogene Proteins
- Protein Kinase B beta
- Rac-PK beta Protein
- Rac PK beta Protein
- AKT2 Protein Kinase
- Akt-beta Protein
- Akt beta Protein
Proto-Oncogene Proteins c-akt3- Proto-Oncogene Proteins c-akt3
- Proteins c-akt3, Proto-Oncogene
- Proto Oncogene Proteins c akt3
- c-akt3, Proto-Oncogene Proteins
- Akt-gamma Protein
- Akt gamma Protein
- AKT3 Protein Kinase
- Protein Kinase B gamma
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-akt".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-akt".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-akt" by people in this website by year, and whether "Proto-Oncogene Proteins c-akt" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 5 | 5 |
| 2005 | 1 | 6 | 7 |
| 2006 | 3 | 4 | 7 |
| 2007 | 2 | 3 | 5 |
| 2008 | 4 | 5 | 9 |
| 2009 | 1 | 8 | 9 |
| 2010 | 0 | 2 | 2 |
| 2011 | 2 | 3 | 5 |
| 2012 | 1 | 2 | 3 |
| 2013 | 2 | 6 | 8 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 5 | 6 |
| 2016 | 2 | 2 | 4 |
| 2017 | 0 | 5 | 5 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 2 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 3 | 0 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-akt" by people in Profiles.
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Unraveling the AKT/ERK cascade and its role in Parkinson disease. Arch Toxicol. 2024 Oct; 98(10):3169-3190.
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Aberrant activation of AXL may drive progression of squamous cell carcinoma in CLL patients: a mechanistic study with clinical implications. Br J Cancer. 2024 Aug; 131(3):589-600.
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Niclosamide causes lysosome-dependent cell death in endometrial cancer cells and tumors. Biomed Pharmacother. 2023 May; 161:114422.
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AKT1 Transcriptomic Landscape in Breast Cancer Cells. Cells. 2022 Jul 25; 11(15).
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Idelalisib activates AKT via increased recruitment of PI3Kd/PI3Kß to BCR signalosome while reducing PDK1 in post-therapy CLL cells. Leukemia. 2022 07; 36(7):1806-1817.
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Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-ß Signaling Axis in Pancreatic Cancer. Gastroenterology. 2022 06; 162(7):2004-2017.e2.
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Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family. Fam Cancer. 2022 07; 21(3):347-355.
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Myocardial Hypertrophy and Compensatory Increase in Systolic Function in a Mouse Model of Oxidative Stress. Int J Mol Sci. 2021 Feb 18; 22(4).
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Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency. FASEB J. 2020 05; 34(5):6335-6350.
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No evidence of attenuation of placental insulin-stimulated Akt phosphorylation and amino acid transport in maternal obesity and gestational diabetes mellitus. Am J Physiol Endocrinol Metab. 2019 12 01; 317(6):E1037-E1049.