| Item Type | Name |
|
Concept
|
beta-Arrestins
|
|
Concept
|
Glycogen Synthase Kinase 3 beta
|
|
Concept
|
Tenofovir
|
|
Concept
|
ADAMTS13 Protein
|
|
Concept
|
Anemia, Sickle Cell
|
|
Concept
|
Aged
|
|
Concept
|
Anti-Bacterial Agents
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Antioxidants
|
|
Concept
|
Calcinosis
|
|
Concept
|
Calcium
|
|
Concept
|
Alprostadil
|
|
Concept
|
Capillaries
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Adenine
|
|
Concept
|
Carbon Tetrachloride
|
|
Concept
|
Cardiac Output
|
|
Concept
|
Blood Coagulation
|
|
Concept
|
Blood Coagulation Factors
|
|
Concept
|
Blood Platelets
|
|
Concept
|
Bone Marrow Cells
|
|
Concept
|
Carotid Arteries
|
|
Concept
|
Carotid Artery Thrombosis
|
|
Concept
|
Cell Cycle
|
|
Concept
|
Cell Division
|
|
Concept
|
Cell Line, Transformed
|
|
Concept
|
Butyrates
|
|
Concept
|
Biophysics
|
|
Concept
|
Biopsy
|
|
Concept
|
Coronary Vessels
|
|
Concept
|
Cricetulus
|
|
Concept
|
Cysteine
|
|
Concept
|
Encephalomyelitis, Autoimmune, Experimental
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Echocardiography
|
|
Concept
|
Cricetinae
|
|
Concept
|
Humans
|
|
Concept
|
Hematopoietic Stem Cells
|
|
Concept
|
Hemolysis
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Lysine
|
|
Concept
|
Neutrophils
|
|
Concept
|
Leukocytes
|
|
Concept
|
Leukotriene B4
|
|
Concept
|
Isomerism
|
|
Concept
|
Methylation
|
|
Concept
|
Platelet Activating Factor
|
|
Concept
|
Platelet Aggregation
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Middle Aged
|
|
Concept
|
Mitochondria
|
|
Concept
|
Models, Cardiovascular
|
|
Concept
|
Monocytes
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Regional Blood Flow
|
|
Concept
|
Thrombin
|
|
Concept
|
Thrombocytopenia
|
|
Concept
|
Thromboplastin
|
|
Concept
|
Protein Biosynthesis
|
|
Concept
|
Signal Transduction
|
|
Concept
|
CD4-Positive T-Lymphocytes
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Platelet Activation
|
|
Concept
|
Stroke Volume
|
|
Concept
|
Annexin A2
|
|
Concept
|
HIV Protease Inhibitors
|
|
Concept
|
Hypertrophy, Left Ventricular
|
|
Concept
|
Plasminogen Activator Inhibitor 1
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
|
Concept
|
von Willebrand Factor
|
|
Concept
|
HL-60 Cells
|
|
Concept
|
Chemokines
|
|
Concept
|
Chemokine CCL2
|
|
Concept
|
Jurkat Cells
|
|
Concept
|
Mice, SCID
|
|
Concept
|
Proto-Oncogene Proteins c-sis
|
|
Concept
|
Leukotriene C4
|
|
Concept
|
Hemorheology
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Calcineurin
|
|
Concept
|
Receptors, CXCR4
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Heart Valve Prosthesis Implantation
|
|
Concept
|
Protein Binding
|
|
Concept
|
Skin Abnormalities
|
|
Concept
|
NF-E2-Related Factor 2
|
|
Concept
|
Mice
|
|
Concept
|
Rats
|
|
Concept
|
beta-Adrenergic Receptor Kinases
|
|
Concept
|
Proto-Oncogene Proteins c-vav
|
|
Concept
|
Mass Spectrometry
|
|
Concept
|
Transcatheter Aortic Valve Replacement
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Complement C3a
|
|
Concept
|
Complement Membrane Attack Complex
|
|
Concept
|
Factor VIIa
|
|
Concept
|
Factor Xa
|
|
Concept
|
Bone Marrow Transplantation
|
|
Concept
|
Fibroblast Growth Factor 1
|
|
Concept
|
Immunoprecipitation
|
|
Concept
|
Glycogen Synthase Kinase 3
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Platelet Transfusion
|
|
Concept
|
Apolipoprotein B-100
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
Transforming Growth Factor beta1
|
|
Concept
|
Arrestins
|
|
Concept
|
Macrophage Inflammatory Proteins
|
|
Concept
|
Atherosclerosis
|
|
Concept
|
Ritonavir
|
|
Concept
|
Endotoxemia
|
|
Concept
|
Thrombotic Microangiopathies
|
|
Concept
|
Mannose-Binding Protein-Associated Serine Proteases
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Chemokine CCL4
|
|
Concept
|
Protein Transport
|
|
Concept
|
Secretory Vesicles
|
|
Concept
|
Receptors, Interleukin-8B
|
|
Concept
|
Anti-Retroviral Agents
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Biophysical Phenomena
|
|
Concept
|
Smad Proteins
|
|
Concept
|
Smad2 Protein
|
|
Concept
|
Sirtuin 3
|
|
Concept
|
Betacoronavirus
|
|
Concept
|
Proteostasis
|
|
Concept
|
Antiviral Agents
|
|
Concept
|
Aorta
|
|
Concept
|
Aortic Valve
|
|
Concept
|
Aortic Valve Stenosis
|
|
Concept
|
Apolipoproteins E
|
|
Concept
|
Arteriosclerosis
|
|
Concept
|
Autoimmune Diseases
|
|
Concept
|
Cerebrovascular Circulation
|
|
Concept
|
Chemotaxis
|
|
Concept
|
Chemotaxis, Leukocyte
|
|
Concept
|
Disulfides
|
|
Concept
|
Megakaryocytes
|
|
Academic Article
|
Association between shear stress and platelet-derived transforming growth factor-ß1 release and activation in animal models of aortic valve stenosis.
|
|
Academic Article
|
Granule cargo release from bone marrow-derived cells sustains cardiac hypertrophy.
|
|
Academic Article
|
Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells.
|
|
Academic Article
|
Distinct roles of receptor phosphorylation, G protein usage, and mitogen-activated protein kinase activation on platelet activating factor-induced leukotriene C(4) generation and chemokine production.
|
|
Academic Article
|
Platelet-activating factor-induced chemokine gene expression requires NF-kappaB activation and Ca2+/calcineurin signaling pathways. Inhibition by receptor phosphorylation and beta-arrestin recruitment.
|
|
Academic Article
|
Regulation of inflammatory responses.
|
|
Academic Article
|
Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1.
|
|
Academic Article
|
Platelet TGF-ß1 contributions to plasma TGF-ß1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload.
|
|
Academic Article
|
Inhibition of tissue factor signaling suppresses tumor growth.
|
|
Academic Article
|
Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1.
|
|
Academic Article
|
In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1.
|
|
Academic Article
|
Cooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice.
|
|
Academic Article
|
Choice of drugs to manage anthrax.
|
|
Academic Article
|
HIV protease inhibitor ritonavir induces renal fibrosis and dysfunction: role of platelet-derived TGF-ß1 and intervention via antioxidant pathways.
|
|
Academic Article
|
Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor ß1 (TGF-ß1) activation.
|
|
Academic Article
|
In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1.
|
|
Academic Article
|
Costimulatory role of CXCR4 with pre-TCR and its crosstalk with PI3K in beta-selection of thymocytes.
|
|
Academic Article
|
Detection of tissue factor antigen and coagulation activity in coronary artery thrombi isolated from patients with ST-segment elevation acute myocardial infarction.
|
|
Academic Article
|
Role of Platelet-Derived Transforming Growth Factor-ß1 and Reactive Oxygen Species in Radiation-Induced Organ Fibrosis.
|
|
Academic Article
|
HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-ß1 and can be suppressed by exogenous carbon monoxide.
|
|
Academic Article
|
New methodologies to accurately assess circulating active transforming growth factor-ß1 levels: implications for evaluating heart failure and the impact of left ventricular assist devices.
|
|
Academic Article
|
Platelet TGF-ß1 deficiency decreases liver fibrosis in a mouse model of liver injury.
|
|
Academic Article
|
Severe aortic stenosis patient risk during the COVID-19 pandemic.
|
|
Academic Article
|
Role of leukotriene B4 receptors in the development of atherosclerosis: potential mechanisms.
|
|
Academic Article
|
Inactivation of platelet-derived TGF-ß1 attenuates aortic stenosis progression in a robust murine model.
|
|
Academic Article
|
Oscillatory shear potentiates latent TGF-ß1 activation more than steady shear as demonstrated by a novel force generator.
|
|
Academic Article
|
Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain.
|
|
Academic Article
|
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling.
|
|
Academic Article
|
C3a enhances nerve growth factor-induced NFAT activation and chemokine production in a human mast cell line, HMC-1.
|
|
Academic Article
|
Signaling of the tissue factor coagulation pathway in angiogenesis and cancer.
|
|
Academic Article
|
Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78.
|
|
Academic Article
|
Disulfide isomerization switches tissue factor from coagulation to cell signaling.
|
|
Academic Article
|
Evidence for activation of tissue factor by an allosteric disulfide bond.
|
|
Academic Article
|
Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia.
|
|
Academic Article
|
Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system.
|
|
Grant
|
The Role of TGF-beta Activation and Signaling in Aortic Stenosis Progression
|
|
Academic Article
|
Tissue factor upregulation is associated with SARS-CoV-2 in the lungs of COVID-19 patients.
|
|
Academic Article
|
L-SIGN is a receptor on liver sinusoidal endothelial cells for SARS-CoV-2 virus.
|
|
Academic Article
|
Megakaryocyte/platelet-derived TGF-ß1 inhibits megakaryopoiesis in bone marrow by regulating thrombopoietin production in liver.
|
|
Academic Article
|
Premortem Skin Biopsy Assessing Microthrombi, Interferon Type I Antiviral and Regulatory Proteins, and Complement Deposition Correlates with Coronavirus Disease 2019 Clinical Stage.
|
|
Academic Article
|
C5b-9 and MASP2 deposition in skin and bone marrow microvasculature characterize hematopoietic stem cell transplant-associated thrombotic microangiopathy.
|
|
Academic Article
|
Long COVID endotheliopathy: hypothesized mechanisms and potential therapeutic approaches.
|
|
Academic Article
|
Endothelial VWF is critical for the pathogenesis of vaso-occlusive episode in a mouse model of sickle cell disease.
|
|
Academic Article
|
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves.
|