Dopamine and cAMP-Regulated Phosphoprotein 32
"Dopamine and cAMP-Regulated Phosphoprotein 32" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoprotein that was initially identified as a major target of DOPAMINE activated ADENYLYL CYCLASE in the CORPUS STRIATUM. It regulates the activities of PROTEIN PHOSPHATASE-1 and PROTEIN KINASE A, and it is a key mediator of the biochemical, electrophysiological, transcriptional, and behavioral effects of DOPAMINE.
| Descriptor ID |
D051937
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| MeSH Number(s) |
D12.776.631.249 D12.776.744.459
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| Concept/Terms |
Dopamine and cAMP-Regulated Phosphoprotein 32- Dopamine and cAMP-Regulated Phosphoprotein 32
- Dopamine and cAMP Regulated Phosphoprotein 32
- Dopamine and cAMP-Regulated Phosphoprotein
- Dopamine and cAMP Regulated Phosphoprotein
- DARPP-32 Protein
- DARPP 32 Protein
- Dopamine and Adenosine 3',5'-Monophosphate-Regulated Phosphoprotein
- Dopamine and Adenosine 3',5' Monophosphate Regulated Phosphoprotein
- Dopamine- and Cyclic AMP-Regulated Phosphoprotein Mr 32,000
- Dopamine and Cyclic AMP Regulated Phosphoprotein Mr 32,000
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Below are MeSH descriptors whose meaning is more general than "Dopamine and cAMP-Regulated Phosphoprotein 32".
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dopamine and cAMP-Regulated Phosphoprotein 32" by people in Profiles.
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DARPP32, a target of hyperactive mTORC1 in the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2022 08 16; 119(33):e2207489119.
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Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat Med. 2011 Dec 18; 18(1):153-8.
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A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures. J Neurosci. 1993 Jul; 13(7):3064-74.