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Brown, Kevin

One or more keywords matched the following items that are connected to Brown, Kevin

Item Type	Name
Concept	Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Concept	Serine-Arginine Splicing Factors
Concept	Poly (ADP-Ribose) Polymerase-1
Concept	Amphetamines
Concept	Analysis of Variance
Concept	Adolescent Behavior
Concept	Anesthesia
Concept	Africa, Eastern
Concept	Anions
Concept	Aged
Concept	Aged, 80 and over
Concept	Alanine Transaminase
Concept	Alcohol Drinking
Concept	Antigens, Differentiation, T-Lymphocyte
Concept	Antineoplastic Combined Chemotherapy Protocols
Concept	Calcium
Concept	Calmodulin
Concept	Alzheimer Disease
Concept	Ambulances
Concept	Acid-Base Equilibrium
Concept	Canada
Concept	Capillary Permeability
Concept	Amino Acid Sequence
Concept	Actins
Concept	Acute Disease
Concept	Acylation
Concept	Adenosine
Concept	Cyclic AMP
Concept	Adenosine Diphosphate
Concept	Carcinoma, Basal Cell
Concept	Carcinoma, Renal Cell
Concept	Blood
Concept	B-Lymphocytes
Concept	Bone Neoplasms
Concept	Base Sequence
Concept	Brain Neoplasms
Concept	Benzhydryl Compounds
Concept	Cell Differentiation
Concept	Cell Line, Transformed
Concept	Cell Movement
Concept	Cell Nucleus
Concept	Cytoskeleton
Concept	Dacarbazine
Concept	Binding Sites
Concept	Butadienes
Concept	Biopsy
Concept	Denmark
Concept	Chromatin
Concept	Chromatography, Gel
Concept	Chromatography, High Pressure Liquid
Concept	Chromatography, Liquid
Concept	Community Participation
Concept	Chromosomes, Human
Concept	Chromosomes, Human, Pair 1
Concept	Chromosomes, Human, Pair 14
Concept	Chromosomes, Human, Pair 18
Concept	Chromosomes, Human, Pair 20
Concept	Chromosomes, Human, Pair 5
Concept	Chromosomes, Human, Pair 6
Concept	Chromosomes, Human, Pair 7
Concept	Chromosomes, Human, Pair 9
Concept	Cooperative Behavior
Concept	Dental Restoration, Permanent
Concept	Creatinine
Concept	Cross-Cultural Comparison
Concept	Diabetes Mellitus, Type 2
Concept	Exons
Concept	Cysteine
Concept	Color
Concept	Energy Transfer
Concept	Family
Concept	Enhancer Elements, Genetic
Concept	Feeding Behavior
Concept	Enzyme Activation
Concept	Enzyme-Linked Immunosorbent Assay
Concept	Doxorubicin
Concept	Finland
Concept	Ethyl Methanesulfonate
Concept	Cyclic GMP
Concept	Guanosine Triphosphate
Concept	Histones
Concept	Health Services Research
Concept	Humans
Concept	Hot Temperature
Concept	Genetic Markers
Concept	Genetics, Population
Concept	HeLa Cells
Concept	Hydrogen Peroxide
Concept	Cholesterol, LDL
Concept	Killer Cells, Natural
Concept	Lymphocytes
Concept	Glycosylation
Concept	Insulin-Like Growth Factor II
Concept	Leukocytes
Concept	Leukocytes, Mononuclear
Concept	Intestine, Small
Concept	Myosins
Concept	Introns
Concept	Nucleic Acid Hybridization
Concept	Ion Channels
Concept	Necrosis
Concept	Obesity
Concept	Methotrexate
Concept	Tissue Plasminogen Activator
Concept	Mice, Inbred BALB C
Concept	Mice, Inbred C57BL
Concept	Mice, Inbred Strains
Concept	Mice, Nude
Concept	Mice, Transgenic
Concept	Middle Aged
Concept	Mitochondria
Concept	Phosphorylation
Concept	Mothers
Concept	Phylogeny
Concept	Papio
Concept	Saccharomyces cerevisiae
Concept	Regulatory Sequences, Nucleic Acid
Concept	Parkinson Disease
Concept	Repetitive Sequences, Nucleic Acid
Concept	Patient Acceptance of Health Care
Concept	Retrospective Studies
Concept	Sequence Homology, Nucleic Acid
Concept	Serine
Concept	Ribonucleoproteins
Concept	Serum Albumin
Concept	Risk-Taking
Concept	RNA Splicing
Concept	Purinones
Concept	T-Lymphocytes
Concept	T-Lymphocytes, Cytotoxic
Concept	Tooth
Concept	Toxoplasma
Concept	Transcription, Genetic
Concept	Rats, Inbred BN
Concept	Quinolones
Concept	Organelles
Concept	Signal Transduction
Concept	Receptors, Androgen
Concept	Xanthines
Concept	Leukemia, Lymphocytic, Chronic, B-Cell
Concept	CD4-Positive T-Lymphocytes
Concept	Down-Regulation
Concept	Zebrafish
Concept	Observer Variation
Concept	Blotting, Western
Concept	Gene Products, tat
Concept	Antigens, CD
Concept	Focus Groups
Concept	Cohort Studies
Concept	Tachycardia, Ventricular
Concept	Rats, Sprague-Dawley
Concept	Apoptosis
Concept	Succinate Dehydrogenase
Concept	Neurofibrillary Tangles
Concept	Interleukin-11
Concept	Alternative Splicing
Concept	CD2 Antigens
Concept	Conserved Sequence
Concept	Codon, Nonsense
Concept	Cyclin-Dependent Kinases
Concept	CD8-Positive T-Lymphocytes
Concept	Microsatellite Repeats
Concept	CpG Islands
Concept	Dinucleotide Repeats
Concept	ras Proteins
Concept	Zinc Fingers
Concept	Open Reading Frames
Concept	Anesthetics, Inhalation
Concept	Lymphoma, Large B-Cell, Diffuse
Concept	Entorhinal Cortex
Concept	Telomerase
Concept	DNA Methylation
Concept	Mice, SCID
Concept	Chromosome Segregation
Concept	Catalytic Domain
Concept	RNA-Binding Proteins
Concept	Telomere
Concept	Interleukin-17
Concept	Databases, Genetic
Concept	Mice, Knockout
Concept	Ryanodine Receptor Calcium Release Channel
Concept	Phosphatidylinositol 3-Kinases
Concept	Paneth Cells
Concept	Cyclin D1
Concept	Cyclin-Dependent Kinase Inhibitor p16
Concept	Mitogen-Activated Protein Kinase 1
Concept	Promoter Regions, Genetic
Concept	Calcium Signaling
Concept	Base Pairing
Concept	Receptor, Adenosine A1
Concept	BRCA2 Protein
Concept	Prospective Studies
Concept	Protein Binding
Concept	Protein Kinase C
Concept	S-Phase Kinase-Associated Proteins
Concept	Proto-Oncogene Proteins c-akt
Concept	Skin Pigmentation
Concept	Smoking
Concept	Social Facilitation
Concept	Mice
Concept	Rats
Concept	Sodium Chloride
Concept	Hepatocyte Nuclear Factor 1-beta
Concept	Small-Conductance Calcium-Activated Potassium Channels
Concept	Adenosine A1 Receptor Agonists
Concept	Purinergic P1 Receptor Antagonists
Concept	Activating Transcription Factor 2
Concept	Mass Spectrometry
Concept	Sphingosine
Concept	Comparative Genomic Hybridization
Concept	Biomarkers, Tumor
Concept	Tumor Necrosis Factor-alpha
Concept	Ultraviolet Rays
Concept	United States
Concept	Protein Stability
Concept	RNA, Small Interfering
Concept	Body Mass Index
Concept	Multivariate Analysis
Concept	Case-Control Studies
Concept	Nonsense Mediated mRNA Decay
Concept	Nucleotide Motifs
Concept	Transcriptome
Concept	Exome
Concept	Telomere Homeostasis
Concept	CDC2 Protein Kinase
Concept	Pulmonary Surfactant-Associated Protein A
Concept	Protein Kinase Inhibitors
Concept	Immunoprecipitation
Concept	Estrogen Receptor alpha
Concept	Proto-Oncogene Proteins p21(ras)
Concept	Extracellular Signal-Regulated MAP Kinases
Concept	Age of Onset
Concept	Proto-Oncogene Proteins B-raf
Concept	Papio anubis
Concept	MAP Kinase Kinase Kinase 5
Concept	Cell Proliferation
Concept	Blood-Borne Pathogens
Concept	Phosphotransferases (Alcohol Group Acceptor)
Concept	Proteomics
Concept	Cyclic GMP-Dependent Protein Kinases
Concept	Janus Kinase 1
Concept	Antiporters
Concept	Tandem Mass Spectrometry
Concept	Receptors, Interleukin-17
Concept	Computational Biology
Concept	BRCA1 Protein
Concept	Transforming Growth Factor beta1
Concept	Genes, BRCA1
Concept	Pathology, Molecular
Concept	Antibodies, Neutralizing
Concept	Proto-Oncogene Proteins c-ets
Concept	STAT3 Transcription Factor
Concept	Suppressor of Cytokine Signaling Proteins
Concept	Interferon Regulatory Factors
Concept	RNA Stability
Concept	HEK293 Cells
Concept	Epigenomics
Concept	Mitogen-Activated Protein Kinases
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	MAP Kinase Kinase Kinases
Concept	MAP Kinase Signaling System
Concept	tat Gene Products, Human Immunodeficiency Virus
Concept	rho-Associated Kinases
Concept	Tacrolimus Binding Protein 1A
Concept	Clustered Regularly Interspaced Short Palindromic Repeats
Concept	RNA Splice Sites
Concept	Myxovirus Resistance Proteins
Concept	Sumoylation
Concept	Cell Line, Tumor
Concept	Microphthalmia-Associated Transcription Factor
Concept	Early Growth Response Protein 1
Concept	Basic Helix-Loop-Helix Transcription Factors
Concept	Hypoxia-Inducible Factor 1
Concept	Hypoxia-Inducible Factor 1, alpha Subunit
Concept	Young Adult
Concept	Benzodioxoles
Concept	P-type ATPases
Concept	Atlases as Topic
Concept	Australia
Concept	Cerebellar Neoplasms
Concept	Cholesterol, Dietary
Concept	Disease Susceptibility
Concept	District of Columbia
Concept	DNA Transposable Elements
Concept	DNA Repair
Concept	DNA Helicases
Concept	Florida
Concept	Follow-Up Studies
Concept	Hydroxylation
Concept	Illinois
Concept	Imidazoles
Concept	Immunohistochemistry
Concept	Indoleacetic Acids
Concept	Melanins
Concept	Optic Nerve
Concept	Ovariectomy
Concept	Oxadiazoles
Concept	Oxygen
Academic Article	Developmental expression of Toll-like receptors-2 and -4 in preterm baboon lung.
Academic Article	Epithelin/granulin growth factors: extracellular cofactors for HIV-1 and HIV-2 Tat proteins.
Academic Article	Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia.
Academic Article	Occurrence of NKX3.1 C154T polymorphism in men with and without prostate cancer and studies of its effect on protein function.
Academic Article	Qualitative research in a cross-cultural context: Fijian experiences.
Academic Article	Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P1 receptor activation.
Academic Article	Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies.
Academic Article	Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.
Academic Article	A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury.
Academic Article	Critical role of interleukin-17A in murine intestinal ischemia-reperfusion injury.
Academic Article	Critical role of interleukin-11 in isoflurane-mediated protection against ischemic acute kidney injury in mice.
Academic Article	Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii.
Academic Article	A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis.
Academic Article	SDHD Promoter Mutations Ablate GABP Transcription Factor Binding in Melanoma.
Academic Article	Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii.
Academic Article	Calmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondii.
Academic Article	Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies.
Academic Article	Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes.
Academic Article	Sex specific associations in genome wide association analysis of renal cell carcinoma.
Academic Article	Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses.
Academic Article	Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma.
Academic Article	Urinary organic anion excretion in response to dietary acid and base loading.
Academic Article	Maternal acceptability of a dietary intervention designed to lower children's intake of saturated fat and cholesterol: the Dietary Intervention Study in Children (DISC).
Academic Article	Automated detection of prevalent mutations in BRCA1 and BRCA2 genes, using a fluorogenic PCR allelic discrimination assay.
Academic Article	No missense mutation of WKL1 in a subgroup of probands with schizophrenia.
Academic Article	Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling.
Academic Article	An expression signature classifies chemotherapy-resistant pediatric osteosarcoma.
Academic Article	Human heat shock protein 27 overexpressing mice are protected against hepatic ischemia and reperfusion injury.
Academic Article	Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling.
Academic Article	A versatile gene-based test for genome-wide association studies.
Academic Article	Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.
Academic Article	Genome-wide association study identifies three new melanoma susceptibility loci.
Academic Article	Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk.
Academic Article	Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma.
Academic Article	Interleukin-11 protects against renal ischemia and reperfusion injury.
Academic Article	The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Academic Article	Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases.
Academic Article	Identification of a melanoma susceptibility locus and somatic mutation in TET2.
Academic Article	Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
Academic Article	Computational and human observer image quality evaluation of low dose, knowledge-based CT iterative reconstruction.
Academic Article	Germline TERT promoter mutations are rare in familial melanoma.
Academic Article	Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
Academic Article	Loci associated with skin pigmentation identified in African populations.
Academic Article	Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations.
Academic Article	Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma.
Academic Article	The genomic and epigenomic evolutionary history of papillary renal cell carcinomas.
Academic Article	Thymic stromal cells in culture. 2. Binding of normal thymocytes to a cloned thymic stromal cell line.
Academic Article	A cholesterol-lowering diet does not produce adverse psychological effects in children: three-year results from the dietary intervention study in children.
Academic Article	Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease.
Academic Article	Effects of beta-estradiol and bisphenol A on heat shock protein levels and localization in the mouse uterus are antagonized by the antiestrogen ICI 182,780.
Academic Article	The use of gene expression analysis to gain insights into signaling mechanisms of metastatic medulloblastoma.
Academic Article	Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure.
Academic Article	Inter-platform comparability of microarrays in acute lymphoblastic leukemia.
Academic Article	Sarcoidosis: social predictors of severity at presentation.
Academic Article	Gene expression correlates of neurofibrillary tangles in Alzheimer's disease.
Academic Article	Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment.
Academic Article	Should all patients with duodenal adenocarcinoma be considered for aggressive surgical resection?
Academic Article	Common sequence variants on 20q11.22 confer melanoma susceptibility.
Academic Article	Genome-wide association study identifies three loci associated with melanoma risk.
Academic Article	Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.
Academic Article	The role of DNA microarrays in Toxoplasma gondii research, the causative agent of ocular toxoplasmosis.
Academic Article	Cytokines induce small intestine and liver injury after renal ischemia or nephrectomy.
Academic Article	A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.
Academic Article	Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury.
Academic Article	The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.
Academic Article	IL-11 is required for A1 adenosine receptor-mediated protection against ischemic AKI.
Academic Article	Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions.
Academic Article	Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.
Academic Article	An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations.
Academic Article	Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii.
Academic Article	A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.
Academic Article	Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148.
Academic Article	Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma.
Academic Article	Essential cGMP Signaling in Toxoplasma Is Initiated by a Hybrid P-Type ATPase-Guanylate Cyclase.
Academic Article	High-Throughput Measurement of Microneme Secretion in Toxoplasma gondii.
Academic Article	Overlapping genetic architecture between Parkinson disease and melanoma.
Academic Article	Correction to: Overlapping genetic architecture between Parkinson disease and melanoma.
Academic Article	Severe autosomal recessive rippling muscle disease.
Academic Article	Variation in the ESR1 and ESR2 genes and genetic susceptibility to anorexia nervosa.
Academic Article	Quantitation of heteroplasmy of mtDNA sequence variants identified in a population of AD patients and controls by array-based resequencing.
Academic Article	Paneth cell-derived interleukin-17A causes multiorgan dysfunction after hepatic ischemia and reperfusion injury.
Academic Article	Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.
Academic Article	The Skp1 protein from Toxoplasma is modified by a cytoplasmic prolyl 4-hydroxylase associated with oxygen sensing in the social amoeba Dictyostelium.
Academic Article	Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia.
Academic Article	Paneth cell-mediated multiorgan dysfunction after acute kidney injury.
Academic Article	Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9.
Academic Article	The effect on melanoma risk of genes previously associated with telomere length.
Academic Article	SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex.
Academic Article	A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue.
Academic Article	Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148.
Academic Article	Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma.
Academic Article	Analysis of NRAS gain in 657 patients with melanoma and evaluation of its sensitivity to a MEK inhibitor.
Academic Article	The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study.
Academic Article	Evaluation of the contribution of germline variants in BRCA1 and BRCA2 to uveal and cutaneous melanoma.
Academic Article	A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeat.
Grant	Non-conventional regulation of essential apicomplexan guanylate cyclases
Academic Article	A large Canadian cohort provides insights into the genetic architecture of human hair colour.
Academic Article	Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family.
Academic Article	Developing youth capacity for community-based research: the Sarasota County demonstration project.
Academic Article	Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1.
Academic Article	Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms.
Academic Article	A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR.
Academic Article	Genomic and evolutionary classification of lung cancer in never smokers.
Academic Article	Prospective, Multicenter, Controlled Trial of Mobile Stroke Units.
Academic Article	Youth and tattoos: what school health personnel should know.
Academic Article	Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals.
Academic Article	Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus.
Academic Article	Toxoplasma bradyzoites exhibit physiological plasticity of calcium and energy stores controlling motility and egress.
Academic Article	Defining novel causal SNPs and linked phenotypes at melanoma-associated loci.
Academic Article	Integrated Analysis of Coexpression and Exome Sequencing to Prioritize Susceptibility Genes for Familial Cutaneous Melanoma.
Academic Article	Investigating the genetic architecture of eye colour in a Canadian cohort.
Academic Article	Rare germline deleterious variants increase susceptibility for lung cancer.
Academic Article	Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity.
Academic Article	Oncogenic CDK13 mutations impede nuclear RNA surveillance.
Academic Article	Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition.
Academic Article	Single-cell profiling of MC1R-inhibited melanocytes.

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Phosphatidylinositol
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Kinase