"Tristetraprolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ZINC FINGER MOTIF containing transcription factor that was originally identified as one of the IMMEDIATE-EARLY PROTEINS. It shuttles between the CYTOPLASM and the CELL NUCLEUS and is involved in destabilization of mRNAs for TUMOR NECROSIS FACTOR-ALPHA.
| Descriptor ID |
D051816
|
| MeSH Number(s) |
D12.776.260.790 D12.776.460.762 D12.776.930.960
|
| Concept/Terms |
Tristetraprolin- Tristetraprolin
- Tristetraprolin Protein
- G0-G1 Switch Regulatory Protein 24
- G0 G1 Switch Regulatory Protein 24
- Zinc Finger Protein 36
|
Below are MeSH descriptors whose meaning is more general than "Tristetraprolin".
Below are MeSH descriptors whose meaning is more specific than "Tristetraprolin".
This graph shows the total number of publications written about "Tristetraprolin" by people in this website by year, and whether "Tristetraprolin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tristetraprolin" by people in Profiles.
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Tristetraprolin Prevents Gastric Metaplasia in Mice by Suppressing Pathogenic Inflammation. Cell Mol Gastroenterol Hepatol. 2021; 12(5):1831-1845.
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Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells. Nat Immunol. 2018 08; 19(8):828-837.
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Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nat Immunol. 2010 Aug; 11(8):717-24.
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HuR and TTP: two RNA binding proteins that deliver message from the 3' end. Gastroenterology. 2009 May; 136(5):1495-8.