"Genomic Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.
| Descriptor ID |
D042822
|
| MeSH Number(s) |
C23.550.362 G05.365.590.335 G05.370
|
| Concept/Terms |
Genomic Instability- Genomic Instability
- Genomic Instabilities
- Instabilities, Genomic
- Instability, Genomic
- Genome Instability
- Genome Instabilities
- Instabilities, Genome
- Instability, Genome
Genomic Stability- Genomic Stability
- Genomic Stabilities
- Stabilities, Genomic
- Stability, Genomic
- Genome Stability
- Genome Stabilities
- Stabilities, Genome
- Stability, Genome
|
Below are MeSH descriptors whose meaning is more general than "Genomic Instability".
Below are MeSH descriptors whose meaning is more specific than "Genomic Instability".
This graph shows the total number of publications written about "Genomic Instability" by people in this website by year, and whether "Genomic Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 2 | 4 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 1 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genomic Instability" by people in Profiles.
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Genomic instability genes in lung and colon adenocarcinoma indicate organ specificity of transcriptomic impact on Copy Number Alterations. Sci Rep. 2022 07 11; 12(1):11739.
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The role of distinct BRD4 isoforms and their contribution to high-grade serous ovarian carcinoma pathogenesis. Mol Cancer. 2021 11 10; 20(1):145.
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XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition. Sci Rep. 2020 08 28; 10(1):14253.
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CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation. J Cell Biol. 2019 04 01; 218(4):1164-1181.
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Mechanisms of Vascular Aging. Circ Res. 2018 09 14; 123(7):849-867.
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DMBA promotes ErbB2-mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability. Oncol Rep. 2018 Sep; 40(3):1632-1640.
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Genome-Wide Mutation Rate Response to pH Change in the Coral Reef Pathogen Vibrio shilonii AK1. mBio. 2017 08 22; 8(4).
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Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer. Carcinogenesis. 2017 01; 38(1):2-11.
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XRN2 Links Transcription Termination to DNA Damage and Replication Stress. PLoS Genet. 2016 07; 12(7):e1006107.
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The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair. Nucleic Acids Res. 2016 Feb 29; 44(4):1718-31.