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Ihnat, Michael
One or more keywords matched the following properties of Ihnat, Michael
PropertyValue
Person ID 3441
One or more keywords matched the following items that are connected to Ihnat, Michael
Item TypeName
Concept Suppressor of Cytokine Signaling 3 Protein
Concept Tartrate-Resistant Acid Phosphatase
Concept Pemetrexed
Concept Polychlorinated Dibenzodioxins
Concept Animal Feed
Concept Histocompatibility Antigens Class II
Concept Antineoplastic Combined Chemotherapy Protocols
Concept Allantoin
Concept Acetylcholinesterase
Concept Acid Phosphatase
Concept Capillary Permeability
Concept Urinary Bladder Neoplasms
Concept Blood Glucose
Concept Bone Marrow Cells
Concept Base Sequence
Concept Cattle
Concept Bromodeoxyuridine
Concept Cell Division
Concept Cell Membrane Permeability
Concept Cytochrome P-450 Enzyme System
Concept Dacarbazine
Concept Chromatin
Concept Chromatography, High Pressure Liquid
Concept Chromium
Concept Clofibrate
Concept Diabetes Mellitus, Experimental
Concept Diabetes Mellitus, Type 1
Concept Diabetes Mellitus, Type 2
Concept Curcumin
Concept Coal
Concept Cyclopentanes
Concept Diabetic Retinopathy
Concept Extracellular Matrix
Concept Cystitis
Concept Collagen
Concept Colonic Neoplasms
Concept Endonucleases
Concept Endothelium, Vascular
Concept Environmental Exposure
Concept Enzyme Activation
Concept Enzyme Induction
Concept Enzyme Inhibitors
Concept Enzyme-Linked Immunosorbent Assay
Concept Doxorubicin
Concept Fibroblasts
Concept Drug Combinations
Concept Drug Evaluation, Preclinical
Concept Drug Screening Assays, Antitumor
Concept Fibrosarcoma
Concept Escherichia coli
Concept Carcinoma, Hepatocellular
Concept Heterocyclic Compounds, 3-Ring
Concept H-2 Antigens
Concept HLA Antigens
Concept Cricetinae
Concept Humans
Concept Hyaluronic Acid
Concept Gene Expression Regulation
Concept Glycated Hemoglobin A
Concept Glioma
Concept Lipopolysaccharides
Concept KB Cells
Concept Glucose
Concept Glucose Tolerance Test
Concept Liver Neoplasms
Concept Liver Neoplasms, Experimental
Concept Lung Neoplasms
Concept Macrophages
Concept Granulocytes
Concept Laminin
Concept Leukocytes, Mononuclear
Concept Nitric Oxide
Concept Mutation
Concept Intestinal Mucosa
Concept Isoenzymes
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Inbred Strains
Concept Mice, Mutant Strains
Concept Mice, Nude
Concept Mice, Transgenic
Concept Microwaves
Concept Mitomycins
Concept Phospholipases A
Concept Pancreatic Neoplasms
Concept Regional Blood Flow
Concept Retina
Concept Sensitivity and Specificity
Concept Risk Factors
Concept Thrombin
Concept Swine
Concept Pyrimidines
Concept Pyrimidinones
Concept Pyrroles
Concept Technetium
Concept Thalidomide
Concept Receptors, GABA-A
Concept Down-Regulation
Concept Androstane-3,17-diol
Concept Blotting, Northern
Concept Blotting, Western
Concept Staining and Labeling
Concept DNA Modification Methylases
Concept Glucose Clamp Technique
Concept Substance P
Concept Paclitaxel
Concept Subtraction Technique
Concept Superoxides
Concept Reactive Oxygen Species
Concept Vasodilation
Concept CD13 Antigens
Concept Drug Resistance, Multiple
Concept Antineoplastic Agents, Alkylating
Concept Gene Expression Regulation, Developmental
Concept Neovascularization, Physiologic
Concept Coculture Techniques
Concept Cell Culture Techniques
Concept Risk Assessment
Concept Drug Resistance, Neoplasm
Concept DNA Adducts
Concept Fluorescent Antibody Technique, Indirect
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Angiogenesis Inhibitors
Concept GTP Phosphohydrolases
Concept Genome
Concept Mitomycin
Concept In Situ Nick-End Labeling
Concept p120 GTPase Activating Protein
Concept DNA, Complementary
Concept Matrix Metalloproteinase 2
Concept Oligonucleotide Array Sequence Analysis
Concept Mice, Knockout
Concept Crystallography, X-Ray
Concept Electron Transport Complex I
Concept Promoter Regions, Genetic
Concept Angiogenesis Inducing Agents
Concept Protease Inhibitors
Concept Proteoglycans
Concept Receptor, PAR-1
Concept Receptor, PAR-2
Concept Mice
Concept Rats
Concept Somatostatin
Concept Halogenation
Concept Umbilical Veins
Concept Serpins
Concept Interleukin-6
Concept Up-Regulation
Concept Tomography, Emission-Computed, Single-Photon
Concept Gene Expression Regulation, Enzymologic
Concept Gene Expression Regulation, Neoplastic
Concept Cluster Analysis
Concept Survival Analysis
Concept Porosity
Concept Polymerase Chain Reaction
Concept Carboplatin
Concept Chromatin Immunoprecipitation
Concept Protein Kinase Inhibitors
Concept Extracellular Signal-Regulated MAP Kinases
Concept Cell Growth Processes
Concept Chorioallantoic Membrane
Concept Cell Proliferation
Concept RANK Ligand
Concept Gene Regulatory Networks
Concept Apolipoprotein B-100
Concept Janus Kinase 2
Concept Genes, Reporter
Concept Computational Biology
Concept Molecular Imaging
Concept STAT3 Transcription Factor
Concept Suppressor of Cytokine Signaling Proteins
Concept Gene Expression Profiling
Concept Xenograft Model Antitumor Assays
Concept Tissue Engineering
Concept Anabolic Agents
Concept Caspase 3
Concept Caspase 7
Concept Smad Proteins
Concept Gene Knockout Techniques
Concept Aldo-Keto Reductase Family 1 Member C3
Concept Aryl Hydrocarbon Hydroxylases
Concept Cell Survival
Concept Chick Embryo
Concept Chickens
Concept Cholinesterase Inhibitors
Concept Disease Models, Animal
Concept DNA, Neoplasm
Concept Docosahexaenoic Acids
Concept Dogs
Concept Fluoresceins
Concept Fluorescent Dyes
Concept Folic Acid Antagonists
Concept Freeze Drying
Concept Furans
Concept Hydroxyquinolines
Concept Hyperglycemia
Concept Hypoglycemia
Concept Immune System
Concept Indazoles
Concept Gas Chromatography-Mass Spectrometry
Concept Mast Cells
Concept Osteoblasts
Concept Osteoclasts
Concept Oxygen
Academic Article The design and discovery of water soluble 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents.
Academic Article A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer.
Academic Article N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastatic and antitumor agents.
Academic Article Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor.
Academic Article Targeting dormant micrometastases: rationale, evidence to date and clinical implications.
Academic Article Antiangiogenic and antitumor agents. Design, synthesis, and evaluation of novel 2-amino-4-(3-bromoanilino)-6-benzylsubstituted pyrrolo[2,3-d]pyrimidines as inhibitors of receptor tyrosine kinases.
Academic Article A novel multidrug resistance phenotype of bladder tumor cells grown on Matrigel or SIS gel.
Academic Article Simultaneous control of hyperglycemia and oxidative stress normalizes enhanced thrombin generation in type 1 diabetes.
Academic Article SOCS3 modulates interleukin-6R signaling preference in dermal fibroblasts.
Academic Article Geochemical characterization and renal cell toxicity of water-soluble extracts from U.S. Gulf Coast lignite.
Academic Article The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity.
Academic Article Binding of nuclear proteins associated with mammalian DNA repair to the mitomycin C-DNA interstrand crosslink.
Academic Article A long-term "memory" of HIF induction in response to chronic mild decreased oxygen after oxygen normalization.
Academic Article Exposure to arsenic at levels found inU.S. drinking water modifies expression in the mouse lung.
Academic Article Blending chitosan with polycaprolactone: porous scaffolds and toxicity.
Academic Article Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation.
Academic Article Laboratory diet profoundly alters gene expression and confounds genomic analysis in mouse liver and lung.
Academic Article Design, synthesis and biological evaluation of substituted pyrrolo[2,3-d]pyrimidines as multiple receptor tyrosine kinase inhibitors and antiangiogenic agents.
Academic Article Design, synthesis and evaluation of 2-amino-4-m-bromoanilino-6-arylmethyl-7H-pyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors and antiangiogenic agents.
Academic Article N4-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: design, synthesis, and in vivo evaluation.
Academic Article Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents.
Academic Article Developmental regulation of the 3-methylcholanthrene- and dioxin-inducible CYP1A5 gene in chick embryo liver in vivo.
Academic Article Effects of mitomycin C and carboplatin pretreatment on multidrug resistance-associated P-glycoprotein expression and on subsequent suppression of tumor growth by doxorubicin and paclitaxel in human metastatic breast cancer xenografted nude mice.
Academic Article Regulatory network of inflammation downstream of proteinase-activated receptors.
Academic Article Repeated BCG treatment of mouse bladder selectively stimulates small GTPases and HLA antigens and inhibits single-spanning uroplakins.
Academic Article The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents.
Academic Article A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model.
Academic Article Transition from androgenic to neurosteroidal action of 5a-androstane-3a, 17ß-diol through the type A ?-aminobutyric acid receptor in prostate cancer progression.
Academic Article Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activity.
Academic Article Mandatory role of proteinase-activated receptor 1 in experimental bladder inflammation.
Academic Article Hypothesis: the 'metabolic memory', the new challenge of diabetes.
Academic Article Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling.
Academic Article Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells.
Academic Article Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors.
Academic Article The contribution of a 2-amino group on receptor tyrosine kinase inhibition and antiangiogenic activity in 4-anilinosubstituted pyrrolo[2,3-d]pyrimidines.
Academic Article Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents.
Academic Article N4-Aryl-6-substitutedphenylmethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as receptor tyrosine kinase inhibitors.
Academic Article AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1a stabilization.
Academic Article Design, synthesis and preclinical evaluation of 5-methyl-N4-aryl-furo[2,3-d]pyrimidines as single agents with combination chemotherapy potential.
Academic Article Structure-activity relationship of glycine betaine analogs on osmotolerance of enteric bacteria.
Grant Drugs Targeting Dormant Tumors as Anti-Metastatic Agents
Academic Article Novel pyrazolo[4,3-d]pyrimidine microtubule targeting agents (MTAs): Synthesis, structure-activity relationship, in vitro and in vivo evaluation as antitumor agents.
Academic Article Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer.
Academic Article Innovative Approaches in the Battle Against Cancer Recurrence: Novel Strategies to Combat Dormant Disseminated Tumor Cells.
Academic Article TNF-Alpha as an Initiator of Allodynia and Anxiety-Like Behaviors in a Preclinical Model of PTSD and Comorbid Pain.
Academic Article 3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity.
Search Criteria
  • Androstane
  • 3
  • 17
  • diol