| Item Type | Name |
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Concept
|
ELAV-Like Protein 1
|
|
Concept
|
Bevacizumab
|
|
Concept
|
A549 Cells
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Administration, Oral
|
|
Concept
|
Anti-Inflammatory Agents
|
|
Concept
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Anti-Bacterial Agents
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Antibodies, Neoplasm
|
|
Concept
|
Antigens, Differentiation
|
|
Concept
|
Antinematodal Agents
|
|
Concept
|
Antineoplastic Agents, Phytogenic
|
|
Concept
|
Caffeine
|
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
|
Concept
|
Blood-Brain Barrier
|
|
Concept
|
Cell Cycle
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Division
|
|
Concept
|
Cell Movement
|
|
Concept
|
Benzylamines
|
|
Concept
|
Dacarbazine
|
|
Concept
|
Chromosomes, Human, Pair 3
|
|
Concept
|
Coronary Vessels
|
|
Concept
|
Cysteine
|
|
Concept
|
Colon
|
|
Concept
|
Combined Modality Therapy
|
|
Concept
|
Endoplasmic Reticulum
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Doxorubicin
|
|
Concept
|
Humans
|
|
Concept
|
HeLa Cells
|
|
Concept
|
Kinetics
|
|
Concept
|
Glycosylation
|
|
Concept
|
Gold
|
|
Concept
|
Maleimides
|
|
Concept
|
Nucleic Acid Hybridization
|
|
Concept
|
Platelet-Derived Growth Factor
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
Mice, Nude
|
|
Concept
|
Phagocytosis
|
|
Concept
|
Mitochondria
|
|
Concept
|
Mitosis
|
|
Concept
|
Spindle Apparatus
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Refractometry
|
|
Concept
|
Periodicals as Topic
|
|
Concept
|
Suspensions
|
|
Concept
|
Transferrin
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Biomarkers
|
|
Concept
|
Receptors, Transferrin
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Colorectal Neoplasms
|
|
Concept
|
Dinoprostone
|
|
Concept
|
Structure-Activity Relationship
|
|
Concept
|
Interleukin-10
|
|
Concept
|
Apoptosis
|
|
Concept
|
Annexin A5
|
|
Concept
|
Cell Death
|
|
Concept
|
Protein Folding
|
|
Concept
|
Chemotherapy, Adjuvant
|
|
Concept
|
Transcription Factor AP-1
|
|
Concept
|
Vitamin E
|
|
Concept
|
Antineoplastic Agents, Alkylating
|
|
Concept
|
Chemokines
|
|
Concept
|
fas Receptor
|
|
Concept
|
src-Family Kinases
|
|
Concept
|
Oligonucleotides, Antisense
|
|
Concept
|
Urinalysis
|
|
Concept
|
RNA-Binding Proteins
|
|
Concept
|
Angiogenesis Inhibitors
|
|
Concept
|
Comet Assay
|
|
Concept
|
Caspases
|
|
Concept
|
Surface Plasmon Resonance
|
|
Concept
|
Matrix Metalloproteinase 2
|
|
Concept
|
Receptors, CXCR4
|
|
Concept
|
Chemokines, CXC
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
eIF-2 Kinase
|
|
Concept
|
Biotinylation
|
|
Concept
|
Endostatins
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Tocopherols
|
|
Concept
|
Protein Binding
|
|
Concept
|
Protein Conformation
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Protein-Tyrosine Kinases
|
|
Concept
|
HMGA1a Protein
|
|
Concept
|
Nanomedicine
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
beta Catenin
|
|
Concept
|
Mitochondrial Membranes
|
|
Concept
|
Mice
|
|
Concept
|
Focal Adhesion Protein-Tyrosine Kinases
|
|
Concept
|
Focal Adhesion Kinase 1
|
|
Concept
|
Triple Negative Breast Neoplasms
|
|
Concept
|
Biomarkers, Tumor
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Exosomes
|
|
Concept
|
Folate Receptors, GPI-Anchored
|
|
Concept
|
Folate Receptor 1
|
|
Concept
|
RNA-Binding Protein FUS
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Cell Cycle Checkpoints
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Biomedical Research
|
|
Concept
|
G2 Phase Cell Cycle Checkpoints
|
|
Concept
|
G1 Phase Cell Cycle Checkpoints
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Resting Phase, Cell Cycle
|
|
Concept
|
G1 Phase
|
|
Concept
|
G2 Phase
|
|
Concept
|
Nanotubes, Carbon
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
Immunoprecipitation
|
|
Concept
|
Chitosan
|
|
Concept
|
MAP Kinase Kinase Kinase 1
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Caspase 9
|
|
Concept
|
Caspase 12
|
|
Concept
|
Spectroscopy, Near-Infrared
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Chemokine CXCL10
|
|
Concept
|
Polycomb Repressive Complex 1
|
|
Concept
|
Chemokine CXCL12
|
|
Concept
|
Active Transport, Cell Nucleus
|
|
Concept
|
Magnetite Nanoparticles
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
TOR Serine-Threonine Kinases
|
|
Concept
|
Caspase 3
|
|
Concept
|
Caspase 7
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Drug Discovery
|
|
Concept
|
Antibodies, Monoclonal, Humanized
|
|
Concept
|
Liquid Biopsy
|
|
Concept
|
Autophagy
|
|
Concept
|
Chemistry, Pharmaceutical
|
|
Concept
|
Cholesterol
|
|
Concept
|
Disulfides
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescamine
|
|
Concept
|
Folic Acid
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Mebendazole
|
|
Concept
|
Membrane Potentials
|
|
Academic Article
|
Chitosan coated polylactic acid nanoparticle-mediated combinatorial delivery of cisplatin and siRNA/Plasmid DNA chemosensitizes cisplatin-resistant human ovarian cancer cells.
|
|
Academic Article
|
Exploitation of Exosomes as Nanocarriers for Gene-, Chemo-, and Immune-Therapy of Cancer.
|
|
Academic Article
|
Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration.
|
|
Academic Article
|
HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy.
|
|
Academic Article
|
Nanodrug delivery systems: a promising technology for detection, diagnosis, and treatment of cancer.
|
|
Academic Article
|
Nanoparticle-based cisplatin therapy for cancer.
|
|
Academic Article
|
Exosomes as Theranostics for Lung Cancer.
|
|
Academic Article
|
Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells.
|
|
Academic Article
|
Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy.
|
|
Academic Article
|
Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy.
|
|
Academic Article
|
HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A.
|
|
Academic Article
|
Regorafenib sensitizes human breast cancer cells to radiation by inhibiting multiple kinases and inducing DNA damage.
|
|
Academic Article
|
Progress in extracellular vesicle biology and their application in cancer medicine.
|
|
Academic Article
|
Exosomes as drug delivery vehicle and contributor of resistance to anticancer drugs.
|
|
Academic Article
|
Combinatorial therapeutic approaches with RNAi and anticancer drugs using nanodrug delivery systems.
|
|
Academic Article
|
Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein HuR.
|
|
Academic Article
|
Chemodrug delivery using integrin-targeted PLGA-Chitosan nanoparticle for lung cancer therapy.
|
|
Academic Article
|
Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment.
|
|
Academic Article
|
Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery.
|
|
Academic Article
|
Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells.
|
|
Academic Article
|
Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy.
|
|
Academic Article
|
Combinatorial Nanoparticle Delivery of siRNA and Antineoplastics for Lung Cancer Treatment.
|
|
Academic Article
|
On the issue of transparency and reproducibility in nanomedicine.
|
|
Academic Article
|
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.
|
|
Academic Article
|
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.
|
|
Academic Article
|
Tumor-Targeted Dendrimer Nanoparticles for Combinatorial Delivery of siRNA and Chemotherapy for Cancer Treatment.
|
|
Academic Article
|
Increased uptake of liposomal-DNA complexes by lung metastases following intravenous administration.
|
|
Academic Article
|
Cytokine- and chemokine-based gene therapy for cancer.
|
|
Academic Article
|
Adenovirus-mediated PTEN treatment combined with caffeine produces a synergistic therapeutic effect in colorectal cancer cells.
|
|
Academic Article
|
Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation.
|
|
Academic Article
|
Local and systemic inhibition of lung tumor growth after nanoparticle-mediated mda-7/IL-24 gene delivery.
|
|
Academic Article
|
MDA-7/IL-24-based cancer gene therapy: translation from the laboratory to the clinic.
|
|
Academic Article
|
Targeted drug and gene delivery systems for lung cancer therapy.
|
|
Academic Article
|
IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis.
|
|
Academic Article
|
Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activity.
|
|
Academic Article
|
Surface plasmon resonance imaging of gold-small molecule interactions is influenced by refractive index and chemical structures.
|
|
Academic Article
|
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
|
|
Academic Article
|
Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo.
|
|
Academic Article
|
Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
|
|
Academic Article
|
Apoptin studies illuminate intersection between lipidomics and tumor suppressors.
|
|
Academic Article
|
mda-7 In combination with bevacizumab treatment produces a synergistic and complete inhibitory effect on lung tumor xenograft.
|
|
Academic Article
|
Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells.
|
|
Academic Article
|
Determinant role for the gep oncogenes, Ga12/13, in ovarian cancer cell proliferation and xenograft tumor growth.
|
|
Academic Article
|
Drug resistance in lung cancer.
|
|
Academic Article
|
Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo.
|
|
Academic Article
|
MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells.
|
|
Academic Article
|
Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.
|
|
Academic Article
|
The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells.
|
|
Academic Article
|
Persistent transgene expression following intravenous administration of a liposomal complex: role of interleukin-10-mediated immune suppression.
|
|
Academic Article
|
Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo.
|
|
Academic Article
|
Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells.
|
|
Academic Article
|
mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
|
|
Academic Article
|
Human interleukin 24 (MDA-7/IL-24) protein kills breast cancer cells via the IL-20 receptor and is antagonized by IL-10.
|
|
Academic Article
|
MDA-7/IL-24 suppresses human ovarian carcinoma growth in vitro and in vivo.
|
|
Academic Article
|
mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
|
|
Academic Article
|
Cancer targeting using tumor suppressor genes.
|
|
Academic Article
|
EGFR-targeted hybrid plasmonic magnetic nanoparticles synergistically induce autophagy and apoptosis in non-small cell lung cancer cells.
|
|
Academic Article
|
Exosomes: a role for naturally occurring nanovesicles in cancer growth, diagnosis and treatment.
|
|
Academic Article
|
HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer.
|
|
Academic Article
|
IL-24 Inhibits Lung Cancer Growth by Suppressing GLI1 and Inducing DNA Damage.
|
|
Academic Article
|
PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.
|
|
Academic Article
|
The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.
|
|
Academic Article
|
mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.
|
|
Academic Article
|
MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
|
|
Academic Article
|
Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells.
|
|
Academic Article
|
Nanoparticle based systemic gene therapy for lung cancer: molecular mechanisms and strategies to suppress nanoparticle-mediated inflammatory response.
|
|
Academic Article
|
Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
|
|
Academic Article
|
Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene.
|
|
Academic Article
|
Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
|
|
Academic Article
|
Inhibition of Src kinase activity by Ad-mda7 suppresses vascular endothelial growth factor expression in prostate carcinoma cells.
|
|
Academic Article
|
Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation.
|
|
Academic Article
|
Vitamin E succinate in combination with mda-7 results in enhanced human ovarian tumor cell killing through modulation of extrinsic and intrinsic apoptotic pathways.
|
|
Academic Article
|
Nanoparticle-mediated gene delivery to the lung.
|
|
Academic Article
|
Structural mapping of post-translational modifications in human interleukin-24: role of N-linked glycosylation and disulfide bonds in secretion and activity.
|
|
Academic Article
|
Mitogen-activated protein kinases and their role in radiation response.
|
|
Academic Article
|
Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activities.
|
|
Academic Article
|
YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways.
|
|
Grant
|
HuR Targeted Nanotherapy for Lung Cancer
|
|
Grant
|
Evaluate the antiangiogenic properties of mda-7/IL-24
|
|
Grant
|
Preclinical Development and Testing of Multifunctional Tumor-Targeted Hybrid Nano
|
|
Academic Article
|
Interleukin (IL)-24: Reconfiguring the Tumor Microenvironment for Eliciting Antitumor Response.
|
|
Academic Article
|
Extracellular Vesicles in Oncology: from Immune Suppression to Immunotherapy.
|
|
Academic Article
|
Drug delivery approaches for HuR-targeted therapy for lung cancer.
|
|
Academic Article
|
Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer.
|
|
Academic Article
|
Investigating Cancerous Exosomes' Effects on CD8+ T-Cell IL-2 Production in a 3D Unidirectional Flow Bioreactor Using 3D Printed, RGD-Functionalized PLLA Scaffolds.
|
|
Academic Article
|
Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment.
|
|
Academic Article
|
RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer.
|