Intracellular Signaling Peptides and Proteins
"Intracellular Signaling Peptides and Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
| Descriptor ID |
D047908
|
| MeSH Number(s) |
D12.644.360 D12.776.476
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Intracellular Signaling Peptides and Proteins".
Below are MeSH descriptors whose meaning is more specific than "Intracellular Signaling Peptides and Proteins".
This graph shows the total number of publications written about "Intracellular Signaling Peptides and Proteins" by people in this website by year, and whether "Intracellular Signaling Peptides and Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 5 | 5 |
| 2000 | 0 | 5 | 5 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 9 | 10 |
| 2003 | 3 | 5 | 8 |
| 2004 | 3 | 2 | 5 |
| 2005 | 3 | 6 | 9 |
| 2006 | 4 | 3 | 7 |
| 2007 | 0 | 2 | 2 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 2 | 4 |
| 2010 | 2 | 4 | 6 |
| 2011 | 7 | 2 | 9 |
| 2012 | 3 | 2 | 5 |
| 2013 | 7 | 0 | 7 |
| 2014 | 6 | 1 | 7 |
| 2015 | 8 | 2 | 10 |
| 2016 | 4 | 0 | 4 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 5 | 2 | 7 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Intracellular Signaling Peptides and Proteins" by people in Profiles.
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Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells. FEBS J. 2021 12; 288(23):6683-6699.
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Genomic locus proteomic screening identifies the NF-?B signaling pathway components NF?B1 and IKBKG as transcriptional regulators of Ripk3 in endothelial cells. PLoS One. 2021; 16(6):e0253519.
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The transcriptional cofactor Jab1/Cops5 is crucial for BMP-mediated mouse chondrocyte differentiation by repressing p53 activity. J Cell Physiol. 2021 08; 236(8):5686-5697.
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The master developmental regulator Jab1/Cops5/Csn5 is essential for proper bone growth and survival in mice. Bone. 2021 02; 143:115733.
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Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical ß-catenin-dependent mechanism. Sci Rep. 2020 06 29; 10(1):10578.
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The crucial p53-dependent oncogenic role of JAB1 in osteosarcoma in vivo. Oncogene. 2020 06; 39(23):4581-4591.
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DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization. Mol Cancer Ther. 2020 07; 19(7):1539-1549.
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KRCC1: A potential therapeutic target in ovarian cancer. FASEB J. 2020 02; 34(2):2287-2300.
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Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion. J Biol Chem. 2019 12 27; 294(52):19950-19966.
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Insights revealed by the co-crystal structure of the Saccharomyces cerevisiae histidine phosphotransfer protein Ypd1 and the receiver domain of its downstream response regulator Ssk1. Protein Sci. 2019 12; 28(12):2099-2111.