Interferon-Stimulated Gene Factor 3
"Interferon-Stimulated Gene Factor 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
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