"Substrate Specificity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
| Descriptor ID |
D013379
|
| MeSH Number(s) |
G02.111.835
|
| Concept/Terms |
Substrate Specificity- Substrate Specificity
- Specificities, Substrate
- Specificity, Substrate
- Substrate Specificities
|
Below are MeSH descriptors whose meaning is more general than "Substrate Specificity".
Below are MeSH descriptors whose meaning is more specific than "Substrate Specificity".
This graph shows the total number of publications written about "Substrate Specificity" by people in this website by year, and whether "Substrate Specificity" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 5 | 5 |
| 1999 | 0 | 9 | 9 |
| 2000 | 0 | 7 | 7 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 7 | 7 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 6 | 6 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 7 | 7 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 7 | 7 |
| 2011 | 0 | 8 | 8 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 5 | 5 |
| 2014 | 0 | 6 | 6 |
| 2015 | 0 | 4 | 4 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 6 | 6 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 3 | 3 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Substrate Specificity" by people in Profiles.
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Evaluation of TrpM and PsiD substrate promiscuity reveals new biocatalytic capabilities. Biotechnol Prog. 2024 Nov-Dec; 40(6):e3492.
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Proteomic approaches for protein kinase substrate identification in Apicomplexa. Mol Biochem Parasitol. 2024 Sep; 259:111633.
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Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus. ACS Chem Biol. 2022 01 21; 17(1):85-102.
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Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence. Biochemistry. 2021 12 14; 60(49):3783-3800.
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A Uniform Benchmark for Testing SsrA-Derived Degrons in the Escherichia coli ClpXP Degradation Pathway. Molecules. 2021 Sep 30; 26(19).
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Acceptor substrate determines donor specificity of an aromatic prenyltransferase: expanding the biocatalytic potential of NphB. Appl Microbiol Biotechnol. 2020 May; 104(10):4383-4395.
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An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s. Sci Rep. 2019 12 02; 9(1):18023.
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RNA-Independent DNA Cleavage Activities of Cas9 and Cas12a. Cell Rep. 2017 12 26; 21(13):3728-3739.
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Kinetic Control of Quorum Sensing in Pseudomonas aeruginosa by Multidrug Efflux Pumps. ACS Infect Dis. 2018 02 09; 4(2):185-195.
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Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner. PLoS One. 2017; 12(11):e0186924.