"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
| Descriptor ID |
D015854
|
| MeSH Number(s) |
G02.111.905 G05.308.850 G07.690.773.998
|
| Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
|
Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 4 | 5 |
| 2003 | 1 | 9 | 10 |
| 2004 | 1 | 7 | 8 |
| 2005 | 0 | 5 | 5 |
| 2006 | 1 | 3 | 4 |
| 2007 | 0 | 9 | 9 |
| 2008 | 2 | 8 | 10 |
| 2009 | 2 | 8 | 10 |
| 2010 | 2 | 3 | 5 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 13 | 13 |
| 2013 | 1 | 6 | 7 |
| 2014 | 3 | 7 | 10 |
| 2015 | 0 | 13 | 13 |
| 2016 | 0 | 8 | 8 |
| 2017 | 0 | 7 | 7 |
| 2018 | 2 | 6 | 8 |
| 2019 | 2 | 4 | 6 |
| 2020 | 3 | 4 | 7 |
| 2021 | 2 | 3 | 5 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism. Mol Cancer Res. 2022 09 02; 20(9):1391-1404.
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Tissue factor upregulation is associated with SARS-CoV-2 in the lungs of COVID-19 patients. J Thromb Haemost. 2021 09; 19(9):2268-2274.
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SIRT3 overexpression and epigenetic silencing of catalase regulate ROS accumulation in CLL cells activating AXL signaling axis. Blood Cancer J. 2021 05 17; 11(5):93.
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17a-Estradiol Modulates IGF1 and Hepatic Gene Expression in a Sex-Specific Manner. J Gerontol A Biol Sci Med Sci. 2021 04 30; 76(5):778-785.
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Colony-stimulating factor 3 signaling in colon and rectal cancers: Immune response and CMS classification in TCGA data. PLoS One. 2021; 16(2):e0247233.
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Upregulation of AXL and ß-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance. Blood Cancer J. 2021 02 18; 11(2):37.
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Augmenting E Protein Activity Impairs cDC2 Differentiation at the Pre-cDC Stage. Front Immunol. 2020; 11:577718.
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Exogenous Thyroid Hormone Is Associated with Shortened Survival and Upregulation of High-Risk Gene Expression Profiles in Steroid Receptor-Positive Breast Cancers. Clin Cancer Res. 2021 01 15; 27(2):585-597.
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Monocyte upregulation of podoplanin during early sepsis induces complement inhibitor release to protect liver function. JCI Insight. 2020 07 09; 5(13).
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Gene expression profiling of tumor stroma interactions in retinoblastoma. Exp Eye Res. 2020 08; 197:108067.