Up-Regulation

"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

Descriptor ID	D015854
MeSH Number(s)	G02.111.905 G05.308.850 G07.690.773.998
Concept/Terms	Up-Regulation Up-Regulation Up Regulation Upregulation Up-Regulation (Physiology) Receptor Up-Regulation Receptor Up-Regulation

Below are MeSH descriptors whose meaning is more general than "Up-Regulation".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Up-Regulation [G02.111.905]
Genetic Phenomena [G05]
Gene Expression Regulation [G05.308]
Up-Regulation [G05.308.850]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacological Phenomena [G07.690.773]
Up-Regulation [G07.690.773.998]

Below are MeSH descriptors whose meaning is related to "Up-Regulation".

Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.

Bar chart showing 165 publications over 24 distinct years, with a maximum of 13 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	0	1	1
1997	1	0	1
1998	0	1	1
2000	0	1	1
2001	0	3	3
2002	1	7	8
2003	1	9	10
2004	1	7	8
2005	0	9	9
2006	2	4	6
2007	0	9	9
2008	1	8	9
2009	2	9	11
2010	1	4	5
2011	0	6	6
2012	1	12	13
2013	1	10	11
2014	3	7	10
2015	0	12	12
2016	0	7	7
2017	0	5	5
2018	2	6	8
2019	2	4	6
2020	2	3	5

Below are the most recent publications written about "Up-Regulation" by people in Profiles.

Xie Z, Shao B, Hoover C, McDaniel M, Song J, Jiang M, Ma Z, Yang F, Han J, Bai X, Ruan C, Xia L. Monocyte upregulation of podoplanin during early sepsis induces complement inhibitor release to protect liver function. JCI Insight. 2020 07 09; 5(13).

View in: PubMed
Raguraman R, Parameswaran S, Kanwar JR, Vasudevan M, Chitipothu S, Kanwar RK, Krishnakumar S. Gene expression profiling of tumor stroma interactions in retinoblastoma. Exp Eye Res. 2020 08; 197:108067.

View in: PubMed
Dang TT, Morales JC. Involvement of POLA2 in Double Strand Break Repair and Genotoxic Stress. Int J Mol Sci. 2020 Jun 15; 21(12).

View in: PubMed
Dunigan-Russell K, Lin V, Silverberg M, Wall SB, Li R, Gotham J, Nicola T, Sridharan A, Snowball J, Delaney C, Li Q, Tipple TE. Aurothioglucose enhances proangiogenic pathway activation in lungs from room air and hyperoxia-exposed newborn mice. Am J Physiol Lung Cell Mol Physiol. 2020 06 01; 318(6):L1165-L1171.

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Ma H, Yang F, Ding XQ. Inhibition of thyroid hormone signaling protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration. Cell Death Dis. 2020 01 13; 11(1):24.

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Awasthi V, Vilekar P, Rao G, Awasthi S. Anti-inflammatory mediators ST2 and SIGIRR are induced by diphenyldifluoroketone EF24 in lipopolysaccharide-stimulated dendritic cells. Immunobiology. 2020 03; 225(2):151886.

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Tryggestad JB, Teague AM, Sparling DP, Jiang S, Chernausek SD. Macrophage-Derived microRNA-155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator-Activated Receptor Gamma. Obesity (Silver Spring). 2019 11; 27(11):1856-1864.

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Wang Y, Hoeppner LH, Angom RS, Wang E, Dutta S, Doeppler HR, Wang F, Shen T, Scarisbrick IA, Guha S, Storz P, Bhattacharya R, Mukhopadhyay D. Protein kinase D up-regulates transcription of VEGF receptor-2 in endothelial cells by suppressing nuclear localization of the transcription factor AP2ß. J Biol Chem. 2019 10 25; 294(43):15759-15767.

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Ade CJ, Bemben DA. Differential MicroRNA expression following head-down tilt bed rest: implications for cardiovascular responses to microgravity. Physiol Rep. 2019 05; 7(9):e14061.

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Ares G, Buonpane C, Sincavage J, Yuan C, Wood DR, Hunter CJ. Caveolin 1 is Associated with Upregulated Claudin 2 in Necrotizing Enterocolitis. Sci Rep. 2019 03 21; 9(1):4982.

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