Promyelocytic Leukemia Protein
"Promyelocytic Leukemia Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
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