I-kappa B Proteins

"I-kappa B Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.

Descriptor ID	D020672
MeSH Number(s)	D12.644.360.365 D12.776.260.420 D12.776.476.381 D12.776.930.326
Concept/Terms	I-kappa B Proteins I-kappa B Proteins I kappa B Proteins I kappa B IkB DNA-Binding Proteins IkB DNA Binding Proteins I-kappa B

Below are MeSH descriptors whose meaning is more general than "I-kappa B Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
I-kappa B Proteins [D12.644.360.365]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
I-kappa B Proteins [D12.776.260.420]
Intracellular Signaling Peptides and Proteins [D12.776.476]
I-kappa B Proteins [D12.776.476.381]
Transcription Factors [D12.776.930]
I-kappa B Proteins [D12.776.930.326]

Below are MeSH descriptors whose meaning is related to "I-kappa B Proteins".

Below are MeSH descriptors whose meaning is more specific than "I-kappa B Proteins".

I-kappa B Proteins
NF-KappaB Inhibitor alpha

publications

Timeline | Most Recent

This graph shows the total number of publications written about "I-kappa B Proteins" by people in this website by year, and whether "I-kappa B Proteins" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2002	1	0	1
2005	0	1	1
2007	0	1	1
2008	0	1	1
2009	0	2	2
2010	1	0	1
2011	0	1	1
2012	1	0	1
2013	0	1	1

Below are the most recent publications written about "I-kappa B Proteins" by people in Profiles.

Pandey MS, Baggenstoss BA, Washburn J, Harris EN, Weigel PH. The hyaluronan receptor for endocytosis (HARE) activates NF-?B-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans. J Biol Chem. 2013 May 17; 288(20):14068-14079.

View in: PubMed
Lee EG, Mickle-Kawar BM, Reinke LA, Gallucci RM. Estrogen suppresses heptatic I?B expression during short-term alcohol exposure. Inflamm Res. 2012 Oct; 61(10):1053-61.

View in: PubMed
Veeraraghavan J, Natarajan M, Lagisetty P, Awasthi V, Herman TS, Aravindan N. Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells. Pancreas. 2011 Oct; 40(7):1107-19.

View in: PubMed
Ponnurangam S, Mondalek FG, Govind J, Subramaniam D, Houchen CW, Anant S, Pantazis P, Ramanujam RP. Urine and serum analysis of consumed curcuminoids using an IkappaB-luciferase surrogate marker assay. In Vivo. 2010 Nov-Dec; 24(6):861-4.

View in: PubMed
Aravindan N, Mohan S, Herman TS, Natarajan M. Nitric oxide-mediated inhibition of NFkappaB regulates hyperthermia-induced apoptosis. J Cell Biochem. 2009 Apr 15; 106(6):999-1009.

View in: PubMed
Aravindan N, Shanmugasundaram K, Natarajan M. Hyperthermia induced NFkappaB mediated apoptosis in normal human monocytes. Mol Cell Biochem. 2009 Jul; 327(1-2):29-37.

View in: PubMed
Fenton JI, Birmingham JM, Hursting SD, Hord NG. Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells. Int J Cancer. 2008 Jun 01; 122(11):2437-45.

View in: PubMed
Rajaiya J, Xiao J, Rajala RV, Chodosh J. Human adenovirus type 19 infection of corneal cells induces p38 MAPK-dependent interleukin-8 expression. Virol J. 2008 Jan 25; 5:17.

View in: PubMed
Oida Y, Gopalan B, Miyahara R, Branch CD, Chiao P, Chada S, Ramesh R. Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation. Mol Cancer Ther. 2007 Apr; 6(4):1440-9.

View in: PubMed
Larabee JL, Hocker JR, Lerner MR, Lightfoot SA, Cheung JY, Brackett DJ, Gallucci RM, Hanas JS. Stress induced in heart and other tissues by rat dermal exposure to JP-8 fuel. Cell Biol Toxicol. 2005 Sep-Nov; 21(5-6):233-46.

View in: PubMed

People

Explore

Similar Concepts

Top Journals