"I-kappa B Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
| Descriptor ID |
D020672
|
| MeSH Number(s) |
D12.644.360.365 D12.776.260.420 D12.776.476.381 D12.776.930.326
|
| Concept/Terms |
I-kappa B Proteins- I-kappa B Proteins
- I kappa B Proteins
- I kappa B
- IkB DNA-Binding Proteins
- IkB DNA Binding Proteins
- I-kappa B
|
Below are MeSH descriptors whose meaning is more general than "I-kappa B Proteins".
Below are MeSH descriptors whose meaning is more specific than "I-kappa B Proteins".
This graph shows the total number of publications written about "I-kappa B Proteins" by people in this website by year, and whether "I-kappa B Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "I-kappa B Proteins" by people in Profiles.
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The hyaluronan receptor for endocytosis (HARE) activates NF-?B-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans. J Biol Chem. 2013 May 17; 288(20):14068-14079.
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Estrogen suppresses heptatic I?B expression during short-term alcohol exposure. Inflamm Res. 2012 Oct; 61(10):1053-61.
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Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells. Pancreas. 2011 Oct; 40(7):1107-19.
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Urine and serum analysis of consumed curcuminoids using an IkappaB-luciferase surrogate marker assay. In Vivo. 2010 Nov-Dec; 24(6):861-4.
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Nitric oxide-mediated inhibition of NFkappaB regulates hyperthermia-induced apoptosis. J Cell Biochem. 2009 Apr 15; 106(6):999-1009.
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Hyperthermia induced NFkappaB mediated apoptosis in normal human monocytes. Mol Cell Biochem. 2009 Jul; 327(1-2):29-37.
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Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia. J Cell Physiol. 2008 Jun; 215(3):771-81.
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Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells. Int J Cancer. 2008 Jun 01; 122(11):2437-45.
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Human adenovirus type 19 infection of corneal cells induces p38 MAPK-dependent interleukin-8 expression. Virol J. 2008 Jan 25; 5:17.
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Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation. Mol Cancer Ther. 2007 Apr; 6(4):1440-9.